产前超声筛查不同年龄段孕妇胎儿畸形的差异性分析  

Defference analysis between fetal malformations and the age of pregnant women by prenatal ultrasonography

作　　者：唐敏[1] 宋建琼[1] 刘梅川 牛亚玲[1] 胡张春 

机构地区：[1]四川省达州市中心医院功能科,635000

出　　处：《临床超声医学杂志》2018年第1期50-53,共4页Journal of Clinical Ultrasound in Medicine

摘　　要：目的分析不同年龄段孕妇产前超声筛查出的胎儿畸形的差异性。方法选取在我院行产前超声筛查的孕妇6119例,按年龄分成≤19岁、20~24岁、25~29岁、30~34岁、35~39岁及≥40岁6组,将产前超声筛查结果与产前诊断中心检查、引产后尸体检查或产后新生儿检查结果进行比较,计算超声筛查胎儿畸形的准确率;分析各组胎儿六大类严重畸形的检出率、畸形数目及畸形类型情况。结果 6119例孕妇共有胎儿畸形204例,超声准确诊断186例(91.18%)。其中,≤19岁组六大类严重畸形检出率最高(53.33%),与其余各组比较差异均有统计学意义(均P<0.05);≥40岁组多发畸形发生率最高(60.00%),但仅与25~29岁组(25.45%)比较差异有统计学意义(P<0.05)。204例胎儿畸形类型以先天性心脏畸形检出数最高,神经系统畸形和颜面部畸形次之。结论孕妇年龄过小容易发生胎儿严重畸形;年龄过大容易发生胎儿多发畸形,且神经系统和先天性心脏畸形的发生几率增高。Objective To analyze the defference between fetal malformations and the different maternal age by prenatal ultrasonography.Methods A total of 6119 pregnant women who proceeded by the prenatal ultrasonography were devided into six groups according to maternal age,including ≤19 years,20 to 24 years,25 to 29 years,30 to 34 years,35 to 39 years and ≥ 40 years.The results of prenatal ultrasonography were compared with those of prenatal diagnosis center＇s examination,necropsy after termination of pregnancy or the postnatal newborn examination.The accuracy rate of fetal malformations diagnosed by prenatal ultrasonography were calculated. The detection rate of six serious malformations,the number and type of fetal malformations in all groups were analyzed.Results There were 204 cases fetal malformations in 6119 pregnant women,186 cases were diagnosed correctly by prenatal ultrasonography（91.18%）.The detection rate of six serious malformations in ≤ 19 years group was the highest.There were significant differences compared with other groups（all P0.05）.The detection rate of multiple malformations in≥ 40 years group was the highest,the difference was statistically significant compared with 25 to 29 years group（P0.05）.The highest fetal malformation was congenital cardiac malformation in the types of fetal malformation,the next was nervous system malformation,facial malformation.Conclusion Younger prenatal women are prone to be detected serious fetal malformations and older prenatal women are prone to be detected fetal multiple malformations.The incidence of nervous system malformation and congenital cardiac malformation of fetuses is higher than the others.

关 键 词：超声检查 胎儿畸形 孕妇年龄 差异性 

分 类 号：R714.5[医药卫生—妇产科学] R445.1[医药卫生—临床医学]