家蚕病原细菌对新蚕药盐酸恩诺沙星可溶性粉药敏性研究  

Study of Silkworm Bacterial Pathogens Sensitivity to a New Silkworm Medicine-Enrofloxacin Hydrochloride Soluble Powder

作　　者：周洪英[1] 孙波[1] 郝瑜[1] 胡兴明[1] 吴洪丽[1] 

机构地区：[1]湖北省农业科学院经济作物研究所,武汉430064

出　　处：《北方蚕业》2017年第4期27-29,54,共4页North Sericulture

基　　金：国家自然科学青年基金(31600010);现代农业产业技术体系建设专项(CARS-18-SYZ11)

摘　　要：为检测盐酸恩诺沙星可溶性粉对家蚕细菌病的抑制作用,采用倍比稀释法进行了体外抑菌实验,测得黑胸败血病和灵菌败血病病原菌共70个菌株的最大MIC值分别为1μg/mL、2μg/mL,低于家蚕添食本药品后最低血药浓度,表明供试菌株对该药品敏感。To test the inhibitive effect of enrofloxacin hydrochloride soluble powder on silkworm bacteriosis,the doubling dilution method was employed to carry out the bacteriostasis test in vitro by determining the minimum inhibitory concentration（MIC）.It was tested that Bacillus spp.and Serratia marcescens（Sm）were major pathogens for silkworms.The highest MIC to seventy tested strains was1μg/ml and 2μg/ml respectively which was lower than the lowest blood concentration after the silkworm were fed medicines.The result shows the tested strains are sensitive to this formulation.

关 键 词：新蚕药 家蚕细菌 药敏性 倍比稀释法 MIC 药代动力学 

分 类 号：S884[农业科学—特种经济动物饲养]