歼击飞行员血清胱抑素C、血肌酐、尿素氮检测的临床意义  

Clinical Significance of Combined Detection of Serum Cystatin C, Serum Creatinine and Urea Nitrogen in Fighter Pilots

作　　者：王萍[1] 谢国乾 孟令龙 朱军波 周京明 潘世鑫[1] 常镜 刘俊[1] 陈正[1] 樊龙中[1] 勉闻光 李民[1] 

机构地区：[1]中国人民解放军422医院检验科,广东湛江524009 [2]中国人民解放军75407部队卫生队 [3]南部战区海军后勤部卫生处 [4]中国人民解放军91878部队 [5]中国人民解放军空军95364部队医院

出　　处：《生物技术通讯》2018年第1期91-93,共3页Letters in Biotechnology

摘　　要：目的:了解歼击飞行员血清胱抑素C(Cys C)、血肌酐(Scr)、尿素氮(BUN)水平及其临床意义。方法:采用乳胶增强比浊法、苦味酸法、酶两点动力法测定歼击飞行员及地勤人员血清Cys C、Scr、BUN浓度。结果:歼击飞行员与地勤人员各项指标比较,差异无统计学意义(P>0.05);二代机飞行员与三代机飞行员各项指标比较,血清Cys C及Scr差异无统计学意义(P>0.05),三代机飞行员BUN比二代机高,差异有统计学意义(P<0.05)。结论:+Gz对高性能战斗机飞行员的肾脏有一过性功能损害,血肌酐尿素氮联合血清胱抑素C检测对评价歼击飞行员的肾功能有积极意义。Objective: To investigate the levels of serum indexes and to clarify the clinical significance in fighter pilots containing serum cystatin C(Cys C), serum creatinine(Scr) and blood urea nitrogen(BUN). Methods: The levels of Cys C, Scr and BUN in fighter pilots and ground crews groups were detected by latex enhanced turbidimetry, picric acid method, and enzyme two-point kinetic method respectively, and the levels between two groups were compared. Results: There was no significant difference between the fighter pilots and ground crew(P>0.05).The levels of Cys C, Scr were not significantly different between the two generation pilots(P>0.05). However, BUN of the third generation pilots was significantly higher than the second generation pilots(P<0.05). Conclusion: +Gz could cause transient impairment to the kidney of high performance fighter pilots. Combined detection of Scr, BUN and Cys C may be positive to evaluate the renal function of fighter pilots.

关 键 词：歼击飞行员 血清胱抑素C 血肌酐 尿素氮 肾功能 

分 类 号：R856[医药卫生—航空、航天与航海医学]