垂体转移癌的诊断、治疗及疗效  

Diagnosis,therapy and therapeutic effect of pituitary metastasis

作　　者：赵奕[1] 连伟[1] 幸兵[1] 姚勇[1] 冯铭[1] 王任直[1] 周炜洵[2] 

机构地区：[1]中国医学科学院北京协和医院神经外科,北京100730 [2]中国医学科学院北京协和医院病理科,北京100730

出　　处：《中华神经外科疾病研究杂志》2018年第1期43-45,共3页Chinese Journal of Neurosurgical Disease Research

摘　　要：目的总结垂体转移癌的诊断、治疗及疗效。方法回顾性分析了1997年4月至2014年8月于北京协和医院神经外科诊断并治疗的垂体转移癌的患者10例。结果男性患者7例(70%),女性患者3例(30%),平均年龄60.4岁。临床表现主要表现为视力障碍者5例(50%)。术后病理回报转移性大细胞肺癌1例(10%),转移性小细胞肺癌2例(20%),转移性肾细胞癌2例(20%),转移性腺癌5例(50%)。随访患者除1例失访外其余9例均得到完全随访,平均存活时间为144 d。结论垂体转移癌是很罕见的疾病,其诊断主要依靠临床特点及影像学检查。其治疗的主要方法为手术加放、化疗等综合治疗。该病的预后较差。Objective The diagnosis, therapy and prognosis of pituitary metastasis were summarized.Methods A total of 10 cases admitted to the Department of Neurosurgery of Peking Union Medical College Hospital （PUMCH） from April 1997 to August 2014 were analyzed retrospectively. Results There were 7 males （70%） and 3 females （30%） with an average age of 60.4 years. The clinical features were visual disabilities （50%）. The post-operative pathology reported that 1 ease （ 10% ） was metastasis of large cell hmg carcinoma, 2 cases （20%） were metastasis of small cell lung carcinoma, 2 cases （20%） were metastasis of renal carcinoma, and5 cases （50%） were metastasis of adenocarcinoma. All cases were thoroughly followed up except for 1 case, and the average survival time was 144 d. Conclusion Pituitary metastasis is a rare disease. The diagnosis of disease mainly depends on the clinical manifestation and radiology. The main therapy method was operation, radiotherapy, and chemotherapy. The prognosis of this disease is poor.

关 键 词：垂体转移癌 诊断 手术 治疗 预后 

分 类 号：R651.13[医药卫生—外科学]