病毒性肝炎肝硬化患者血脂水平与病性类证候要素的关系  

Relationship between lipid levels and class syndrome factors of viral hepatitis in patients with liver cirrhosis

作　　者：崔玮玮[1] 薛晓琳[1] 王天芳[1] 周子严 李鑫 李永纲[2] 陈盛铎[3] 孙凤霞[4] 李秀惠[5] 毛德文[6] 刘燕玲[7] 张厂[8] 刘汶[9] CUI Wei-wei;XUE Xiao-lin;WANG Tian-fang;ZHOU Zi-yan;LI Xin;LI Yong-gang;CHEN Sheng-duo;SUN Feng-xia;LI Xiu-hui;MAO De-wen;LIU Yan-ling;ZHANG Chang;LIU Wen(Beijing University of Chinese Medicine, Beijing 100029, China;Chinese PLA 302 Hospital, Beijing 100039, China;Chinese Medicine Hospital of Hubei Province, Wuhan 430000, China;Beijing Ditan Hospital, Capital Medical University, Beijing 100015, China;SBeijing You＇an Hospital, Capital Medical University, Beijing 100069, Chin;First Affiliated Hospital of Guangxi College of Chinese Medicine, Nanning 530000, China;Xiyuan Hospital Affiliated to China Academy of Traditional Chinese Sciences, Beijing 100091, China;Dongfang Hospital Affiliated to Beijing University of Chinese Medicine, Beijing 100078, China;Beijing Hospital of TCM Affiliated to Capital Medical University, Beijing 100010, China)

机构地区：[1]北京中医药大学,北京100029 [2]中国人民解放军第302医院,北京100039 [3]湖北省中医院,武汉430000 [4]首都医科大学附属北京地坛医院,北京100015 [5]首都医科大学附属北京佑安医院,北京100069 [6]广西中医药大学第一附属医院,南宁530000 [7]中国中医科学院西苑医院,北京100091 [8]北京中医药大学东方医院,北京100078 [9]首都医科大学附属北京中医医院,北京100010

出　　处：《中华中医药杂志》2018年第2期645-648,共4页China Journal of Traditional Chinese Medicine and Pharmacy

基　　金：国家重点基础研究发展计划(973计划)(No.2011CB505105);北京市东城区"中医药特色健康管理社区创建"评估项目(No.2010071620042)~~

摘　　要：目的:研究不同血脂水平病毒性肝炎肝硬化患者的病性辨证结果的分布情况,探讨血脂水平与病性类证候要素的关系。方法:采用流行病学横断面调查方法,收集病毒性肝炎肝硬化患者的相关临床信息,运用SPSS20.0统计软件分析不同血脂水平病性辨证结果的构成比有无差异。结果:不同TC水平,是否判定为气滞、气虚、水停证型,构成比的差异有统计学意义(P<0.01);不同TG水平,是否判定为血瘀、阴虚、水停证型,构成比的差异有统计学意义(P<0.05,P<0.01);不同HDL水平,是否判定为血瘀、阳虚、水停证型,构成比的差异有统计学意义(P<0.05,P<0.01);不同LDL水平,是否判定为阴虚、气滞、阳虚、水停证型,构成比的差异有统计学意义(P<0.01)。结论:不同血脂水平,患者病性辨证结果的构成比有差异,说明病毒性肝炎肝硬化患者的血脂水平可能与肝藏血主疏泄生理功能失调有关。Objective：To study the distributional differences of syndrome differentiation of disease nature in patients with viral hepatitis cirrhosis in different lipid levels,and to explore the relationship between the lipid levels and class syndrome factors.Methods：Cross-sectional epidemiological field survey was adopted to collect the main clinical data of the viral hepatitis cirrhosis patients.The differences of constituent ratio of syndrome differentiation of disease nature were compared by SPSS 20.0.Results：If all patients were grouped according to different TC levels,constituent ratios of qi stagnation and non-qi stagnation,qi deficiency and non-qi deficiency,water retention pattern and non-water retention pattern were different.The above conclusions had statistical significance（P〈0.01）.If all patients were grouped according to different TG levels,constituent ratios of blood stasis and non-blood stasis,yin deficiency and non-yin deficiency,water retention pattern and non-water retention pattern were different.The above conclusions had statistical significance（P〈0.05,P〈0.01）.If all patients were grouped according to different HDL levels,constituent ratios of blood stasis and non-blood stasis,yang deficiency and non-yang deficiency,water retention pattern and non-water retention pattern were different.The above conclusions had statistical significance（P〈0.05,P〈0.01）.If all patients were grouped according to different HDL levels,constituent ratios of yin deficiency and non-yin deficiency,qi stagnation and nonqi stagnation,yang deficiency and non-yang deficiency,water retention pattern and non-water retention pattern were different.The above conclusions had statistical significance（P〈0.01）.Conclusion：Nature of disease causes syndrome differentiation.The constituent ratios of syndrome differentiations are different in different lipid levels,which means blood lipids of patients with viral hepatitis cirrhosis may be related to the dysfunctions of liver storing blood and governing free flo

关 键 词：肝炎肝硬化 血脂 藏象学说 证候要素 

分 类 号：R259[医药卫生—中西医结合]