以宣肺解痉法为基本治法治疗支气管哮喘疗效观察  

Dispering Lung and Relieving Spasm Method in Treatment of Bronchial Asthma

作　　者：郭洁[1] 武蕾[1] 吴丽梅[2] 景璇[3] 梁亚飞[4] 王峥嵘[5] GUO Jie;WU Lei;WU Limei;JING Xuan;LIANG Yafei;WANG Zhengrongs(Respiration Department Two, Hebei Provinieal Hospoital of TCM, Shijiazhuang 050011, Hebei, China;Nursing Department, Hebei Provinieal Hospoital of TCM, Shijiazhuang 050011, Hebei, China;Medical Affairs Department, Hebei Provinical Hospoital of TCM, Shijiazhuang 050011, Hebei, China;Hebei College of TCM, Shijiazhuang 05001 l, Hebei, China;Tumor Department Two, Hebei Provinical Hospoital of TCM, Shijiazhuang 050011, Hebei, China)

机构地区：[1]河北省中医院呼吸二科,河北石家庄050011 [2]河北省中医院护理部,河北石家庄050011 [3]河北省中医院医务处,河北石家庄050011 [4]河北中医学院,河北石家庄050011 [5]河北省中医院肿瘤二科,河北石家庄050011

出　　处：《中华中医药学刊》2018年第2期465-468,共4页Chinese Archives of Traditional Chinese Medicine

基　　金：河北省中医药管理局科研计划项目(2016021);河北省重大医学科研项目(zyzd2013001);河北省政府资助临床医学优秀人才培养项目(2015054965)

摘　　要：目的：观察以宣肺解痉法为基本治法治疗支气管哮喘的临床疗效。方法：选取支气管哮喘患者80例,随机分为治疗组及对照组,每组40例。对照组予西医常规治疗,治疗组在对照组基础上加用宣肺解痉基础方治疗,持续治疗8周。比较两组患者治疗前后血EOS计数、IgE水平,PEF及其变异率,痰LTD4水平,临床症状及有效率。经治疗后随访12月,对病情进行评分并比较。结果：治疗组与对照组治疗前EOS计数、IgE水平、PEF变异率、痰LTD4水平比较无显著性差异（P〉0.05）,经治疗后均较治疗前降低,且治疗组降低更明显（P〈0.05）。治疗组与对照组症状积分比较有显著性差异（P〈0.05）。总有效率明显高于对照组（P〈0.05）。随访结果显示,治疗组病情评分显著低于对照组（P〈0.05）。结论：宣肺解痉法治疗对支气管哮喘疗效显著,具有较高的临床价值,值得进一步推广。Objective ： To observe the curative effect of dispering lung and relieving spasm method as the basic method in the treatment of bronchial asthma. Method ： A total of 80 cases of patients with bronchial asthma were randomly divided into treatment group and control group, 40 cases in each group. The control group was given routine treatment and the treatment group on the basis additionally added Xuanfei Decoction. The therapy lasted for 8 weeks. Two groups were com- pared before and after treatment blood EOS count, the levels of IgE, PEF and its variation rate of sputum LTIM levels, clinical symptoms and efficiency. After treatment and follow - up for 12 months, scores of the disease and the comparison were analyzed. Result：Before treatment, the treatment group and control group＇ s EOS count, IgE level, PEF mutation rate and phlegm LTIM levels had no significant difference （P 〉 0. 05）. After treatment, all were lower than those before treatment, and the treatment group＇ s decreased significantly （P 〈 0. 05 ）. The treatment group and the control group ＇ s symptom scores had significant difference （P 〈^（）. 05）. The total efficiency of the treatment group was significantly higher than that of the control group （ P 〈 0.05 ）. The follow - up results showed that the treatment group＇ s patients were signif- icantly better than the control group＇ s （ P 〈 0. 05 ）. Conclusion： The dispering lung and relieving spasm method has obvi- ous therapeutic effect on bronchial asthma, with a high clinical value, worthy of further promotion.

关 键 词：支气管哮喘 宣肺解痉法 PEF EOS计数 IgG LTD4 

分 类 号：R562.25[医药卫生—呼吸系统]