供者年龄对亲属活体供肾移植效果影响研究  

Effect of donor age on living related renal transplantation

作　　者：郭丰富[1] 张振[1] 付猛 庞爱霞[1] 朱文彬[1] 邵志强[3] 

机构地区：[1]山东省临沂市人民医院泌尿外科,山东临沂276003 [2]北京清华长庚医院泌尿外科,北京102218 [3]解放军总医院第一附属医院泌尿外科,北京100048

出　　处：《中国医学工程》2017年第11期1-3,共3页China Medical Engineering

基　　金：山东省医药卫生科技发展计划面上项目(2011HZ020)

摘　　要：目的探讨不同年龄段供者年龄对活体亲属供肾脏移植效果的影响。方法选择在中国肾脏移植科学登记系统(CSRKT)备案登记的943例活体亲属供肾脏移植数据。按照供者的年龄不同分成≥60岁,50~59岁,40~49岁,30~39岁,<30岁5组,比较受者术后并发症、肾功能及人/肾存活率情况。结果 5组术后急性排斥反应、移植肾功能延迟恢复、肺部感染等主要并发症发生率基本相似,术后1周、1个月、3个月及1年的血肌酐(Scr)及1年人/肾存活率差异均无统计学意义(P>0.05)。结论供者年龄对活体亲属供肾移植术后肾功能恢复及短期疗效无明显影响。[Objective] To compare the results of the living related renal transplantation with donors of different age groups. [Methods] With the authorization from the relevant departments, we chose 943 cases of living related renal transplantation from Chinese Scientific Registry of Kidney Transplantation （CSRKT）. These transplant recipients were divided into five groups according to donor＇s age： group 1 （range, donor＇s age _〉60 years）, group 2 （range, 50-59 years）, group 3 （range, 40-49 years）, group 4 （range, 30-39 years） and group 5 （range, 〈30 years）. Then we compared the serum creatinine （Scr） level of different time （1 week, 1 month, 3 months and 1 year after operation）, operative complications and one-year patient/graft survival rates. [Results] There were no significant difference in Scr between the groups at different time points （P 〉0.05）. The incidence of acute rejection, delayed recovery of renal function, pulmonary infection and other complications and one-year survival rate of human/kidney were similar. [Conclusion] There was no significant difference between different donor age groups in renal function recovery after transplantation and short-term curative effect.

关 键 词：肾移植 活体亲属供者 高龄 终末期肾病 移植效果 

分 类 号：R692.5[医药卫生—泌尿科学]