T1ρ序列、MR和关节镜在膝关节软骨成像中的应用对比  

Comparison of T1ρ, MR and arthroscopy in the diagnosis of knee joint cartilage

作　　者：高丽香 袁慧书[1] 

机构地区：[1]北京大学第三医院放射科,北京100191

出　　处：《实用放射学杂志》2018年第2期256-259,共4页Journal of Practical Radiology

摘　　要：目的 研究T1ρ序列对于膝关节骨关节炎（OA）的诊断价值，并对比T1ρ、MR与关节镜对早期髌骨软骨损伤诊断的敏感性。方法 共扫描28例住院患者的膝关节MRI，经后处理软件处理后，T1ρ序列轴位测量正常与损伤软骨的T1ρ值，所有病例均记录MR和关节镜结果。结果 T1ρ序列可以清晰地显示关节软骨，且呈现不同色阶，正常软骨T1ρ值均＜50 ms，随着软骨损伤的加重T1ρ值逐渐增高，Ⅰ-Ⅱ级与Ⅲ-Ⅳ级软骨的数值差异有统计学意义。其中9例MR和关节镜下均为0级的软骨在T1ρ序列上出现T1ρ值升高，近似于Ⅰ-Ⅱ级软骨损伤，T1ρ序列对于早期软骨损伤的诊断敏感性高于MR与关节镜。另外，关节镜和MR对于软骨的诊断价值存在较高的一致性。结论 T1ρ序列能够无创地、有效地预测膝关节OA；T1ρ序列可先于MR与关节镜发现早期软骨损伤。Objective To explore the value of T1ρ in the diagnosis of knee osteoarthritis（ OA} ,and to compare the diagnostic ability of T1ρ, MR and arthroscopy for early patellar cartilage injury.Methods 28 patients underwent T1ρ MR imaging.We processed the images and measuredT1ρ values of the normal and damage cartilage. All cases were recorded results of MR and arthroscopy.Results T1ρ sequence could show cartilage clearly, and performed different colour levels,T1ρ values of normal cartilage were less than 50 ms, and increased with aggravation of cartilage injury.The differences of Ⅰ-Ⅱ and Ⅲ-Ⅳ had statistically significant.9 cases in grade 0 under MR and arthroscopy performed high values inT1ρ,which similar to grade Ⅰ-Ⅱ injury,the diagnosis sensitivity of T1ρ for early cartilage injury was higher than MR and arthroscopy.In addition, arthroscopy and MR had high consistency in the diagnosis of cartilage.Conclusion T1ρ can effectively predict early cartilage injury and knee OA non-invasively,and can detect early cartilageinjury before MR and arthroscopy.

关 键 词：膝关节 软骨 磁共振成像 关节镜 

分 类 号：R322.72[医药卫生—人体解剖和组织胚胎学] R445.2[医药卫生—基础医学]