新虚拟单能重建结合低浓度对比剂在下肢动脉造影中的可行性研究  

A feasibility study in advanced virtual monoenergetic image reconstruction combined with low concentration of contrast agent in lower extremity CT arteriography

作　　者：唐丽[1] 高剑波[1] 吴艳[1] 刘杰[1] 石惠[1] 

机构地区：[1]郑州大学第一附属医院放射科,河南郑州450052

出　　处：《实用放射学杂志》2018年第2期296-299,共4页Journal of Practical Radiology

摘　　要：目的 探讨双源CT新虚拟单能（mono-plus）重建结合低浓度对比剂在下肢动脉造影中的可行性。方法 收集本院行下肢动脉CT血管造影（CTA）检查患者30例，采用双能模式进行扫描（80/140 snkVp），对比剂（碘克沙醇，350 mg I/mL）总量为1 mg/kg×体质量（kg）。利用双源CT新后处理工作站获得mono-plus 40 keV及50 keV（A、B组）图像，同时利用常规双源后处理工作站（mono）获得最佳对比噪声比（CNR）对应keV图像（C组），比较3组图像组间的CT值、信噪比（SNR）、CNR及图像质量主观评分。结果 A、B组CT值、SNR及CNR均较C组升高（P〈0.001）；3组CT值分别为691.75（571.02~780.57）HU，470.80（399.67~532.10）HU，（279.62±5.15）HU；SNR分别为27.65±0.45，25.45±4.08，20.95±0.33；CNR分别为24.76±4.02，21.94±0.36，16.65±0.28；3组间主观评分差异有统计学意义，主-髂动脉及股-腘动脉段B组评分最高，A组与C组无统计学差异；而在小腿动脉及足部动脉段，A组评分最高，但与B组无统计学差异。结论 mono-plus 40 keV及50 keV可以改善图像质量，并提供了低浓度对比剂的可行性。Objective To explore the feasibility of advanced virtual monoenergetic （mono plus） image reconstruction combined with low concentration of contrast agent in lower extremity computed tomography angiography （CTA）.Methods 30 patients underwent lower extremity arterial CTA were collected in our study.Dual-energy mode （80/140 snkVp） was applied after the administration of 1 mg/kg body weight contrast media （350 mg I/mL）.40 and 50 keV mono-plus images and conventional mono images at optimal keV were reconstructed. The objective image quality of CT value,SNR and CNR as well as subjective image quality between three groups were compared. Results CT value, SNR and CNR of both group A and B were higher than group C （ P〈0.001 ） ; The CT values in three groups were 691.75 （571.02-780.57）HU,470.80（399.67-532.10）HU, （279.62±5.15）HU respectively;SNR were 27.65-0.45,25.45±4.08,20.95±0.33 respectively;CNR were 24.76±4.02, 21.94±0.36, 16.65±0.28 respectively. There were significant differences among the three groups for subjective scores. In the aortoiliac area and femoro popliteal district, the highest score was obtained in group B, no significant difference between group A and group C.ln the erural segment and plantar arteries, the highest score was obtained in group A, but there was no significant difference between group A and group C.Conclusion Mono-plus images at 40 keV and 50 keV levels significantly improve the contrast of lower extremity runoff compared with mono image,and enable a reduction of required contrast media.

关 键 词：下肢动脉 对比剂 新虚拟单能重建 计算机体层成像 血管造影术 

分 类 号：R323.72[医药卫生—人体解剖和组织胚胎学] R814.42[医药卫生—基础医学]