地氟烷与七氟烷用于儿科麻醉的术后恢复效果分析  

Effect of desflurane and sevoflurane on postoperative recovery in pediatric anesthesia

作　　者：徐海峰 闫小辉 王向宇 王开俊[1] 任俏[1] 

机构地区：[1]广东省深圳市罗湖区人民医院麻醉科,518052

出　　处：《中华灾害救援医学》2018年第2期94-96,共3页Chinese Journal of Disaster Medicine

摘　　要：目的分析地氟烷与七氟烷用于儿科麻醉的术后恢复效果,以便指导临床麻醉用药。方法收集2016-01至2017-01深圳市罗湖区人民医院收治的68例手术患儿临床资料。应用地氟烷麻醉的患儿为研究组(n=34),应用七氟烷麻醉的患儿为对照组(n=34)。对比分析两组患儿的术后早期复苏时间、术后恢复时间、不良反应发生率及眼心反射发生率。结果 (1)研究组术后早期复苏时间[(7.68±1.14)min vs(8.29±1.22)min]、术后恢复时间[(47.96±7.15)min vs(52.02±6.97)min]短于对照组,差异均具有统计学意义(t=-2.130,P=0.037;t=-2.371,P=0.021)。(2)研究组术后出现咳嗽屏气1例、体动1例、分泌物增多1例、呕吐2例,对照组出现咳嗽屏气4例、体动3例、分泌物增多3例、呕吐3例,研究组不良反应发生率(14.70%)低于对照组(38.24%),差异具有统计学意义(χ~2=4.836,P=0.028)。(3)研究组眼心反射发生率略低于对照组,但差异无统计学意义(χ~2=0.770,P=0.380)。结论术治疗的患儿以地氟烷吸入方式行麻醉维持时,患儿术后恢复快、不良反应发生率低。Objective The objective of this study was to compare the effects of desflurane and sevoflurane on postoperative recovery in pediatric anesthesia, and to provide guidance for clinical anesthetic medication. Methods A total of 68 children, undergoing surgery in Shenzhen Luohu District People＇s Hospital from January 2016 to January 2017, were retrospectively analyzed. Children being provided with desflurane anesthesia were selected as the research group（n=34）, and children being given sevoflurane anesthesia were chosen as the control group（n=34）. The time taken for early recovery, and for postoperative recovery, incidence of adverse reaction and ocular reflex between the two groups were compared and analyzed. Results（1） The time taken for early recovery in the research group and control group was（7.68±1.14） min vs（8.29±1.22） min, and for the postoperative recovery of the two groups was（47.96±7.15） min vs（52.02±6.97） min. The time taken for early recovery and postoperative recovery of the research group were shorter than those of the control group, and the differences were statistically significant（t=-2.130,P=0.037;t=-2.371,P=0.021）.（2） There were 1 case of cough breath, 1 case of body movement, 1 case of exudates and 2 cases of vomiting in the research group. And 4 cases of cough breath, 3 cases of body movement, 3 cases of exudates and 3 cases of vomiting in the control group. The incidence of adverse reactions in the research group（14.70%） was lower than that of the control group（38.24%）, and the difference was statistically significant（χ~2=4.836,P=0.028）.（3） The incidence of oculocardiac reflex in the research group was slightly lower than that of the control group, but the difference was not statistically significant（χ~2=0.770,P=0.380）. Conclusions When using desflurane inhalation for anesthesia maintenance, children can recover faster and have lower incidence of adverse reactions.

关 键 词：地氟烷 七氟烷 儿科麻醉 术后恢复 

分 类 号：R726.1[医药卫生—儿科]