高压氧联合糖皮质激素救治一氧化碳中毒迟发性脑病效果分析  

Analysis on the effect of hyperbaric oxygen combined with glucocorticoid in the treatment of delayed encephalopathy with carbon monoxide poisoning

作　　者：刘林东[1] 季晓坤 李巧粉 Liu Lindong;Ji Xiaokun;Li Qiaofen(The First People＇s Hospital of Qujing City,Yunnan Province 65500)

机构地区：[1]云南省曲靖市第一人民医院

出　　处：《中国社区医师》2018年第5期41-42,共2页Chinese Community Doctors

摘　　要：目的:探讨高压氧联合糖皮质激素治疗一氧化碳中毒迟发性脑病的效果。方法:收治一氧化碳中毒迟发性脑病患者40例,随机分成观察组和对照组,各20例。对照组给予营养神经、改善循环治疗的同时进行间歇长疗程高压氧治疗,观察组在对照组基础上给予地塞米松。结果:治疗1个疗程、2个疗程和3个疗程后,观察组MMSE评分明显高于对照组(P<0.05),观察组总有效率高于对照组(P<0.05)。结论:高压氧联合糖皮质激素救治一氧化碳中毒迟发性脑病效果显著。Objective：To investigate the effect of hyperbaric oxygen combined with corticosteroid in the treatment of delayed encephalopathy in carbon monoxide poisoning.Methods：40 patients with delayed encephalopathy after carbon monoxide poisoning were selected.They were randomly divided into the observation group and the control group with 20 cases in each group.The control group were given nerve nutrition,improve the treatment cycle,and taken long intermittent courses of hyperbaric oxygen therapy at the same time.The observation group were given dexamethasone based on the treatment given in the control group.Results：After 1 course,2 courses and 3 courses,the MMSE score in the observation group was significantly higher than that in the control group（P0.05）,and the total effective rate in the observation group was higher than that in the control（P0.05）.Conclusion：Hyperbaric oxygen combined with glucocorticoid in treating delayed encephalopathy of carbon monoxide poisoning has significantly effect.

关 键 词：高压氧 糖皮质激素 急性一氧化碳中毒迟发性脑病 

分 类 号：R595.1[医药卫生—内科学] R747.9[医药卫生—临床医学]