四级厌氧系统处理螺旋霉素发酵废水的中试研究（英文）  

Pilot Scale Treatment of Spiramycin Fermentation Wastewater in Four-stage Anaerobic System(FSAS)

作　　者：刘鹏宇[1] 邵雷[1] 姚健[2] 陈佳容[1] 陈代杰[1,3] 

机构地区：[1]中国医药工业研究总院上海医药工业研究院,创新药物与制药工艺国家重点实验室,上海201203 [2]中国药科大学生命科学与技术学院,江苏南京210009 [3]上海交通大学药学院,上海200240

出　　处：《中国医药工业杂志》2018年第2期156-162,共7页Chinese Journal of Pharmaceuticals

摘　　要：在废水处理过程中,为提高螺旋霉素发酵废水的厌氧降解效率,采用四级厌氧系统对其进行处理,连续监测了134 d内不同有机负荷条件下系统各级的p H值、化学需氧量(COD)及螺旋霉素残留量的变化情况。结果表明,当四级厌氧系统的厌氧停留时间为12 d时,进水平均COD为11 320 mg/L,处理后出水平均COD为1 023 mg/L,COD去除率达91%。通过四级厌氧系统的降解处理后,废水中残留的螺旋霉素浓度从41.8降至11.3 mg/L。采用生物检测法检测系统出水,未检测到抗菌活性。在螺旋霉素废水的处理过程中,四级厌氧系统表现出较高的COD去除效率及残留螺旋霉素的降解效果,可为抗生素废水的厌氧处理提供新思路。To improve the anaerobic digestion efficiency of spiramycin fermentation wastewater, the stability and performance of a pilot-scale four-stage anaerobic system （FSAS） were studied at different organic loading rates （OLR） for 134 d. In the process of OLR lifting, indicators such as pH value, chemical oxygen demand （COD）, and spiramycin concentration were observed. The results showed that when the average influent COD was 11 320 mg/L at the hydraulic retention time （HRT） of 12 d, the average effluent COD was 1 023 mg/L and COD removal efficiency reached 91%.In the anaerobic digestion, it was found that spiramycin was degraded from 41.8 mg/L to 11.3 mg/L and its antibacterial activity could not be detected through antimicrobial susceptibility testing after the treatment by FSAS. In the process of spiramycin wastewater treatment, FSAS had the advantage of high COD removal efficiency and residual spiramycin degradation, which could provide some guidance for the anaerobic treatment of antibiotic wastewater.

关 键 词：厌氧降解 四级厌氧系统 螺旋霉素 化学需氧量 废水 

分 类 号：TQ469[化学工程—制药化工]