皮肤再生医疗技术治疗痛风性溃疡的临床疗效  

The Clinical Effect of Skin Regenerative Medical Technology in the Treatment of Gout Ulcer

作　　者：李杰辉[1] 刘雪琴 狄钾骐[1] 张春霞[1] 刘明[1] 

机构地区：[1]广西中医药大学第一附属医院,广西南宁530023 [2]广西中医药大学,广西南宁530021

出　　处：《中国烧伤创疡杂志》2018年第1期12-16,共5页The Chinese Journal of Burns Wounds & Surface Ulcers

基　　金：国家自然科学基金(81660793);2017年中国红十字基金会徐荣祥再生生命公益基金科研项目(2017-02)~~

摘　　要：目的观察皮肤再生医疗技术治疗痛风性溃疡的临床疗效。方法对2016年1月—2017年10月广西中医药大学第一附属医院收治的20例痛风性溃疡患者在全身综合治疗的基础上,创面采用皮肤再生医疗技术治疗,观察临床疗效。结果治疗2周后,20例患者中痊愈1例,显效4例,有效15例,总显效率为25%,总有效率为100%;治疗4周后,20例患者中痊愈10例,显效9例,有效1例,总显效率为95%,总有效率为100%。治疗前后,患者体内ALT、AST、BUN及Cr水平均无明显变化,经多样本均数比较的方差分析,F值分别为0.905、0.684、0.016、0.080,P均>0.05,差异无统计学意义,而血尿酸水平明显降低,F=7.157,P<0.05,差异具有统计学意义。结论皮肤再生医疗技术治疗痛风性溃疡,可有效促进创面愈合,疗效显著,且操作简便,值得临床推广应用。Objective To observe the clinical effect of regenerative medical technology in the treatment of gout ul- cer. Methods 20 patients with gout ulcer, admitted to The First Affiliated Hospital of Guangxi University of Chinese Medi- cine from January 2016 to October 2017 received systemic therapy. In addition to that, skin regenerative medical technology was given. The clinical efficacy was observed. Results After 2 weeks of treatment, 1 of the 20 patients healed, 4 im- proved markedly and 15 got effective result. The total marked effective rate was 25% and the total effective rate was 100%. After 4 weeks of treatment, 10 of the 20 patients healed, 9 improved markedly and 1 got effective resuh. The total marked effective rate was 95% and the total effective rate was 100%. Before and after the treatment, no significant change in the average level of ALT, AST, BUN and Cr in patients was observed. Variance analysis showed no statistically significant difference （ F values =0. 905, O. 684, 0. 016 and 0. 080, all P 〉0. 05）. Uric acid level decreased markedly and the corn-parison showed statistically significant difference （ F = 7. 157, P 〈 0. 05）. Conclusion The clinical efficacy of the skin re- generative medical technology is excellent in treating gout ulcer with a simple operational procedure, which can be promoted in the clinical practice.

关 键 词：皮肤再生医疗技术 湿润烧伤膏 痛风性溃疡 疗效 临床研究 

分 类 号：R589.7[医药卫生—内分泌] R632.1[医药卫生—内科学]