成都地区干部保健人群缺血性心脑血管病的5年随访研究  

Five-year follow-up of ischemic cardiocerebrovascular diseases in Chengdu pediatric healthcare people

作　　者：秦地茂[1] 蔡琳[1] 王晓梅 刘汉雄[1] 汪汉[1] 余秀琼[1] 蒋晖[1] 熊峰[1] 罗媛[2] 

机构地区：[1]成都市第三人民医院心内科,610031 [2]成都市第三人民医院干部保健科,610031

出　　处：《中华老年心脑血管病杂志》2018年第2期168-170,共3页Chinese Journal of Geriatric Heart,Brain and Vessel Diseases

基　　金：四川省干部保健科研课题(ZB2014-05)

摘　　要：目的探讨成都地区干部保健人群5年缺血性心脑血管病发病率以及相关危险因素。方法采用回顾性队列研究方法,分析我院2011~2016年有连续随访数据的干部保健人群822例,根据诊断分为冠心病组43例,非冠心病组779例。多因素分析缺血性心脑血管病的相关危险因素。结果 822例有连续随访数据的受试者,5年缺血性心脑血管病发病率为523人/10万,年发病率为104人/10万。冠心病组年龄、糖尿病、空腹血糖、肌酐水平明显高于非冠心病组[(71.26±9.61)岁vs(63.81±9.79)岁,P=0.000;20.5%vs 8.2%,P=0.045;(6.38±2.48)mmol/L vs(5.09±1.10)mmol/L,P=0.000;(80.47±20.87)μmol/L vs(74.81±15.10)μmol/L,P=0.020]。logistic回归分析显示,年龄、吸烟与空腹血糖与缺血性心脑血管病密切相关(OR=1.104,95%CI:1.057~1.154,P=0.000;OR=2.219,95%CI:1.018~4.835,P=0.045;OR=1.564,95%CI:1.320~1.852,P=0.000)。结论干部保健人群缺血性心脑血管病发病率偏低,主要与增龄、高血糖以及吸烟相关。Objective To study the prevalence of ischemic cardiocerebrovascular disease （ICVD） and its risk factors in Chengdu pediatric heahhcare people. Methods A total of 822 pediatric healthcare people in our hospital were divided into coronary heart disease （CHD） group （n=43） and CHD-free group （n=779）. Their consecutive data from 2011 to 2016 were retrospectively analyzed. The risk factors for ICVD were analyzed by multivariate regression analysis. Results CHD was detected in 523 out of 100 000 cases in 5 years and in 104 out of 100 000 cases in each year. The age was significantly older, the incidence of DM and the serum FBG and Cr levels were significantly higher in CHD group than in CHD-free group （71.26±9. 61 vs 63.81±9. 79,P= 0. 000 ; 20.5% vs 8.2 % , P = 0.045 ; 6.38 ± 2.48 mmol/L vs 5.09± 1.10 mmol/L, P = 0. 000 ; 80.47± 20.87 μmol/L vs 74. 81 ± 15. 10 μmol/L, P = 0. 020）. Logistic regression analysis showed that age,smoking, and serum FBG level were closely associated with ICVD （OR= 1. 104, 95%CI： 1. 057-1. 154,P=0.000;OR=2.219,95% CI：1.018-4.835,P=0.045 ; OR=1.564,95% CI. 1. 320- 1. 852, P = 0. 000）. Conclusion The prevalence of ICVD is relatively low in pediatric heahhcare people, which is closely associated with age, smoking and hyperglycemia.

关 键 词：脑血管障碍 心血管疾病 糖尿病 吸烟 肥胖症 危险因素 

分 类 号：R54[医药卫生—心血管疾病] R743[医药卫生—内科学]