稽留流产发病因素临床分析  

The clinical analysis for the etiological factors of missed abortion

作　　者：张艺玮[1] 郝亚楠[2] 潘晓伟 

机构地区：[1]河北省石家庄市第一医院妇科,050011 [2]河北省石家庄市第一医院超声科,050011

出　　处：《河北医药》2018年第3期413-415,420,共4页Hebei Medical Journal

基　　金：石家庄市科学技术研究与发展指导计划项目(编号:151461313)

摘　　要：目的探讨稽留流产发生的危险因素,减少再次稽留流产的发生。方法采用统一信息调查表对2013年1月至2014年12月于石家庄市第一医院初治的200例稽留流产患者进行问卷调查,对所得数据使用SPSS 11.0软件进行统计分析。结果发现稽留流产的常见原因为感染,占31.5%。26~30岁、31~35岁年龄段稽留流产的发生率明显增高。人工流产的次数越多,发生稽留流产的几率越大。200例患者血清中钙、铁、锌、锂的含量均低于正常值占总数的90%,差异有统计学意义(P<0.05)。200例患者中,低孕酮者发生稽留流产占总数48%,高泌乳素者占总数30%,低雌激素者占总数10%,差异有统计学意义(P<0.05)。结论防治生殖道感染、纠正孕妇的免疫状态、远离高辐射环境可降低孕早期稽留流产的发生。足量的微量元素浓度和性激素水平对胚胎发育和妊娠的维持有极为重要的作用。建议最佳生育年龄为25~29岁,珍惜每一次受孕机会,减少盲目的人工流产,对稽留流产的发生也有重要意义。Objective To investigate the risk factors of missed abortion to decrease the incidence of repeated abortions. Methods A questionnaire survey was performed for 200 patients with missed abortion who were treated firstly in our hospital from January 2013 to December 2014. The results were statistically analyzed by SPSS 11. 0 software. Results The common cause of missed abortion was the infection factors,which accounted for 31. 5%. The incidence of missed abortion was significantly increased in the age range of 26 ~ 30 years and 31 ~ 35 years. The more the number of times of artificial abortion,the higher the probability of incidence of missed abortion. Among 200 patients,the patients whose serum levels of calcium,iron,zinc and lithium were lower than the normal value accounted for 90%,and the difference was statistically significant（ P 〈0. 05）. Among 200 patients,the patients with lower levels of progesterone who had missed abortion accounted for 48%,the patients with high levels of lactotropin accounted for 30%,and the patients with low levels of estrogens accounted for 30%,the difference was statistically significant（ P 〈0. 05）. Conclusion Preventing genital tract infection,improving the immune status of pregnant women and avoiding high radiation environment can reduce the incidence rate of missed abortion in early pregnancy. The sufficient trace element concentration and sex hormone levels play an important role in embryo development and maintenance of pregnancy. It is suggested that the best child-bearing age should be 25 ~ 29 years,and it is important to cherish every chance of conception and reduce blindly induced abortion.

关 键 词：稽留流产 胚胎停育 发病因素 性激素 感染 微量元素 

分 类 号：R714.21[医药卫生—妇产科学]