Padua预测评分在AECOPD住院患者VTE风险因素分析中的应用  

Application of Padua predictive score in VTE risk factors analysis of AECOPD inpatients

作　　者：李星晶[1] 沈芳[1] 王鹏[1] 

机构地区：[1]上海市第一人民医院宝山分院呼吸科,上海200940

出　　处：《临床肺科杂志》2018年第3期453-456,共4页Journal of Clinical Pulmonary Medicine

摘　　要：目的应用Padua预测评分分析慢性阻塞性肺疾病急性加重期(AECOPD)住院患者VTE的危险因素,探讨对VTE筛选的价值。方法回顾性调查呼吸科198例次AECOPD住院患者,均做过VTE的影像学检查。选取其中合并VTE的患者65例作为VTE组,133例不存在VTE的住院患者为无VTE组,采用回顾性病例对照分析研究,统计相关危险因素,进行Padua预测评分,分析高危、低危(Padua评分≥4分、<4分)与实际发生VTE的相关性。结果 Padua预测评分≥4分的患者有130例(65.65%),多元线性回归分析显示:高Padua得分的相关因素有6个,包括活动度降低≥3天、活动性肿瘤、激素治疗、高龄(≥70岁)、心/呼吸衰竭、急性感染,与性别无关;VTE组和无VTE组进行OR值(95%CI)分析提示高危级发生VTE的风险较高,具有统计学意义。结论 AECOPD患者存在较高的VTE风险,应用Padua评分可以有效地进行VTE危险评估,评估方法量化、方便,适用于临床。Objective To analyze the application of Padua predictive score in VTErisk factors analysis ofAECOPDinpatients. Methods The clinical data of 198 AECOPDinpatients were retrospectively analyzed,who allreceived VTE imaging examination. 65 patients complicated with VTEwere selected as the VTE group,and the rest133 patients without VTE were taken as the non-VTE group. Retrospective case-control study wascores of the two groups with high risk and low risk （ Padua score≥4 ,〈 4 ） and the actual occurrence of VTE correlation. Results Judged by Padua prediction score, 6 5.65% patients had a high risk for VTE （ Padua score ≥4 ） .Multiple linear regression analysis showed that there were 6 factors related to high Padua scores,includinductions≥ 3 days,active tumors,hormone therapy,a ge,heart/lung failure,acute infection and gender independence. The OR value （95% CI） analysis between the study group and the control group suggested that the risk of VTE was higher at the high risk group,which was statistically significant. Conclusion AECOPD patients have a higher risk of VTE,and Padua predictive score can be effective in assessing the risk factors quantify and suitable for clinical use.

关 键 词：慢性阻塞性肺疾病 Padua预测评分 静脉血栓栓塞症 危险因素 

分 类 号：R563.9[医药卫生—呼吸系统]