TCT、高危HPV分型检测联合阴道镜检查在宫颈癌筛查中的应用价值  

Application value of TCT,high-risk HPV genotyping detection combined with colposcopy in cervical cancer screening

作　　者：由月兰 初悦美[1] 荆翠红 邢金磊 

机构地区：[1]海阳市人民医院妇科,山东海阳265100

出　　处：《中国妇幼保健》2018年第2期452-454,共3页Maternal and Child Health Care of China

摘　　要：目的讨论宫颈癌筛查中TCT、高危HPV分型检测联合阴道镜检查的应用价值。方法选取2014年6月-2016年12月在海阳市人民医院经早期筛查疑似为宫颈癌的患者342例,先施行TCT联合HPV-DNA分型检测,后施行阴道镜检测,对检测结果进行比较。结果 TCT、HPV-DNA分型联合阴道镜检测对重度不典型性增生、中度不典型性的增生、轻度不典型性增生的检出率大于TCT联合HPV-DNA分型检测,差异有统计学意义(P<0.05)。结论使用TCT、HPV-DNA分型联合阴道镜可以更有效的检验宫颈癌,具有重要的临床诊断价值。Objective To explore the application value of Thinprep cytology test（TCT）,high-risk human papillomavirus（HPV）genotyping detection combined with colposcopy in cervical cancer screening.Methods A total of 342 patients suspected of cervical cancer through early screening in Haiyang Municipal People＇s Hospital from June 2014 to December 2016 were selected,TCT combined with HPVDNA genotyping detection was performed,then colposcopy was performed,the results were compared.Results The detection rates of severe,moderate,and mild atypical hyperplasia by TCT,HPV-DNA genotyping detection combined with colposcopy were statistically significantly higher than those by TCT combined with HPV-DNA genotyping detection（P〈 0.05）.Conclusion TCT,HPV-DNA genotyping detection combined with colposcopy can more effectively detect cervical cancer,which have important clinical diagnostic value.

关 键 词：宫颈癌 TCT HPV-DNA分型 阴道镜 

分 类 号：R711[医药卫生—妇产科学]