支气管内纤维瘤致反复阻塞性肺炎1例并文献复习  

Recurrent obstructive pneumonia caused by endobronchial fibroma： a case report and literature review

作　　者：王东昌[1] 赵瑞贞[1] 赵云霞[1] 王玲婵 陈刚[1] Wang Dongchang;Zhao Ruizhen;Zhao Yunxia;Wang Lingchan;Chen Gang(The First Department of Respiratory Medicine, the Third Hospital of Hebei Medical University, Shijiazhuang 050051, China)

机构地区：[1]河北医科大学第三医院呼吸一科,石家庄050051 [2]河北医科大学第三医院超声科,石家庄050051

出　　处：《国际呼吸杂志》2018年第1期20-25,共6页International Journal of Respiration

摘　　要：目的提高对支气管内纤维瘤的认识，提高疾病诊断率。方法结合河北医科大学第三医院呼吸一科收治的1例支气管内纤维瘤患者，复习相关英文文献对支气管内纤维瘤进行分析。结果9例患者中，男7例，女2例，平均年龄（45±12）岁，主要症状包括咳嗽、胸闷、咯血、发热、胸痛等。瘤体位于气管、主支气管、叶支气管。4例胸部CT发现气管支气管内肿物影，3例经支气管镜活检病理诊断。4例经支气管镜介入治疗，5例行外科手术治疗。结论支气管内纤维瘤是一种极其罕见的疾病，其临床表现及影像学表现无特异性，不易与其他气道内肿瘤相鉴别，需结合组织病理及免疫组织化学结果明确诊断。对于反复发生同一部位肺炎患者应行支气管镜排查气道内肿瘤。支气管内纤维瘤治疗方法可选用支气管镜下高频电凝圈套肿物切除。Objective To enhance the understanding of endobronchial fibroma and improve the diagnosis rate of the disease. Methods One patient with endobronchial fibroma treated in the Third Hospital of Hebei Medical University was reported, and the published literatures in English were reviewed. Results Seven male and two female patients were included,with a mean age of （45-^-12） years old. The main symptoms included cough, chest tightness, hemoptysis, fever, chest pain. The tumors were found in the trachea, main bronchi and lobular bronchi. Chest CT showed endobronchial lump shadow in four cases, and three patients were diagnosed by pathological examination of the transbronchial biopsy specimen. Interventional therapy by bronchoscopy was carried out in four cases. Five patients underwent surgical resection. Conclusions Endobronchial fibroma is a rare disease, the clinical and imaging features are nonspecific. It is difficult to distinguish with other tumors in the airway. It is necessary to make a definite diagnosis with histopathological and immunohistochemical findings. For recurrent pneumonia in the same site, bronchoscopy should be performed. Endobronchial fibroma can be treated with high frequency electrocoagulation snare under bronchoscope.

关 键 词：纤维瘤 支气管镜 阻塞性肺炎 

分 类 号：R563.1[医药卫生—呼吸系统] R734.1[医药卫生—内科学]