两个C_(19)-二萜生物碱的结构鉴定和NMR信号归属（英文）  

Structural Elucidation and NMR Spectral Assignments of Two C_(19)-Diterpenoid Alkaloids

作　　者：尹田鹏[1,2] 陈阳[1] 罗萍 蔡乐[2] 丁中涛[2] 

机构地区：[1]遵义医学院珠海校区,珠海市中药基础及应用研究重点实验室,广东珠海519041 [2]云南大学化学科学与工程学院,云南省高校功能分子分析与生物转化重点实验室,云南昆明650091

出　　处：《波谱学杂志》2018年第1期90-97,共8页Chinese Journal of Magnetic Resonance

基　　金：The national natural science foundation of China (81460648); Graduate student quality curriculum of Yunnan university.

摘　　要：从剑川乌头(Aconitum handelianum)的根中分离得到两个C_(19)-二萜生物碱:高展花乌头宁(homochasmanine,化合物1)和14-去苯甲酰大渡乌碱(14-debenzoylfranchetine,化合物2).采用1D和2D核磁共振(NMR)技术(包括~1H NMR、^(13)C NMR、DEPT、~1H-~1H COSY、HSQC、HMBC和NOESY)对其进行结构鉴定,完整归属了这两个化合物的~1H和^(13)C NMR信号.Two C19-diterpenoid alkaloids, homochasmanine （compound 1） and 14-debenzoylfranchetine （compound 2）, were isolated from the roots of Aconitum handelianum. Their structures were elucidated by one-dimensional and two-dimensional nuclear magnetic resonance （NMR） techniques, including ^1H NMR, ^13C NMR, DEPT, ^1H-^1H COSY, HSQC, HMBC and NOESY. The ^1H and ^13C NMR signals of the compounds were completely assigned.

关 键 词：核磁共振(NMR) 鉴定 归属 二萜生物碱 剑川乌头(Aconitum handelianum) 

分 类 号：O482.53[理学—固体物理]