他汀类药物与运动关系的研究进展  

Advances in the relationship between statins drugs and physical activities

作　　者：窦鸿伟 陈亮[1] 阚通 秦永文[1] 

机构地区：[1]第二军医大学长海医院心血管内科,上海200433

出　　处：《药学服务与研究》2018年第1期38-41,共4页Pharmaceutical Care and Research

基　　金：国家自然科学基金(81470407)

摘　　要：他汀类药物可能产生肌肉相关性不良反应,本文回顾他汀类药物与运动之间的关系。他汀类药物的应用对服药者的心肺适能、运动表现和运动耐力无明显影响,但对肌肉力量可能产生不利影响仍未达成共识。运动训练时使用他汀类药物虽有不良事件发生,但能够更有效地降低心血管疾病的风险。Statins drugs may induce muscle-associated adverse reactions.The paper reviewed the relationship between statins and physical activities.The medication of statins has no obvious effects on cardiorespiratory function,athletic performance and exercise tolerance.However,there is no agreement so far as to its adverse effects on muscle strength.In spite of the fact that the application of statins during physical exercise may induce adverse events,it could effectively reduce the risk of cardiovascular disease.

关 键 词：他汀类 运动 肌肉力量 他汀相关肌肉症状 综述 

分 类 号：R972.6[医药卫生—药品] R994.11[医药卫生—药学]