缓解期支气管哮喘行气道反应性测定临床价值研究  

Study on the clinical value of airway responsiveness in bronchial asthma in remission stage

作　　者：林嘉镖[1] 王桂兰[1] 黄东明[1] 黄娟[1] 刘翔腾[1] 

机构地区：[1]广东省中山市博爱医院,广东中山528403

出　　处：《中国医药科学》2018年第3期199-201,共3页China Medicine And Pharmacy

基　　金：广东省中山市医学科研项目(2015A020132)

摘　　要：目的对缓解期支气管哮喘行气道反应性和肺功能进行测定探讨其临床价值。方法选取我院呼吸科门诊2015年10月~2016年6月符合本次实验的患者40例,将全部患儿自身的肺部功能施以评测,选出成果最优值即评测成果。选出第一秒呼吸容积(FEV1)、用力肺活量(FVC)及最大呼气流量(PEF),V25%~75%的流速值,再进行支气管激发试验。结果通过对40例缓解期支气管哮喘儿童肺功能测定,肺功能患者异常31例,正常9例;而对患儿进行支气管激发试验中,其中阳性患者5例,阴性35例。肺功能异常组与肺功能正常组激发试验阳性率比较差异有统计学意义(P<0.01)。结论支气管哮喘缓解期患者气道高反应持续的时间较长,所以我们应该提早给予患者规范化治疗,需长期维持治疗;定期复查肺功能有助于指导缓解期治疗,从而降低患者气道反应性。Objective To evaluate the clinical value of airway responsiveness and pulmonary function in remission bronchial asthma. Methods Forty patients were selected from the respiratory clinic of our hospital from October 2015 to June 2016.All the children's lung function was evaluated,the best value of the results that evaluation results was selected.The first second forced expiratory volume(FEV1),forced vital capacity(FVC) and peak expiratory flow(PEF),V25%-75% flow value were selected,and the bronchial provocation test was carried out. Results By measuring lung function of 40 children with bronchial asthma in remission stage,31 cases of pulmonary function were abnormal and 9 cases were normal.In the bronchial provocation test of children,5 cases were positive and 35 cases were negative.There was a significant difference in the positive rate between the abnormal lung function group and the normal lung function group(P < 0.01). ConclusionThe airway hyperresponsiveness of patients with bronchial asthma in remission period lasts a long time,so we should give patients standardized treatment early,need to maintain treatment for a long time;Regular reexamination of lung function helps to guide remission treatment and reduce airway responsiveness in patients.

关 键 词：?哮喘 肺功能 气道高反应性 支气管激发试验 

分 类 号：R562.25[医药卫生—呼吸系统]