海洋中药厚藤的化学成分及药理活性研究进展  

Research progress on chemical constituents of marine medicine Ipomoea pes-caprae and their pharmacological activities

作　　者：冯小慧 邓家刚[1,2] 秦健峰 郝二伟 韦玮[1,2] 谢金玲 侯小涛[1,2] 

机构地区：[1]广西中医药大学,广西南宁530200 [2]广西中药药效研究重点实验室,广西南宁530200

出　　处：《中草药》2018年第4期955-964,共10页Chinese Traditional and Herbal Drugs

基　　金：广西科学研究与技术开发计划项目(桂科合15104001-11);广西科学研究与技术开发计划项目(2017AD19024);广西中药药效研究重点实验室建设项目(16-380-29);农作物废弃物功能成分研究协同创新中心建设项目(CICAR 2017-Y1)

摘　　要：厚藤Ipomoea pes-caprae为旋花科(Convolvulaceae)番薯属植物,是一种生长于滨海滩涂的海洋植物药,不仅是我国南方沿海民间常用海洋中药和京族习用植物药,同时,也是澳大利亚、墨西哥、泰国、巴西、巴基斯坦等多个热带及亚热带国家的传统药用植物。其资源丰富,应用广泛。其化学成分主要包括树脂糖苷类、萜类、黄酮类、酚酸类、挥发性成分、甾体类等。现代药理研究表明厚藤具有抗肿瘤、抗菌、抗炎镇痛、抗胶原酶、抗氧化、免疫调节等多种药理活性。深入总结厚藤的化学成分及药理活性的研究现状,以期为该海洋中药的临床应用、质量控制和产品开发等提供参考。Ipornoea pes-caprae, the plant of Ipomoea （Convolvulaceae）, is the marine medicine growing in the intertidal zone of coasts. It is not only the Jing nationality medicine in the southern coastal areas of China, but also the folk medicine in the tropical and subtropical countries such as Australia, Mexico, Thailand, Brazil, and Pakistan. It is resource-rich and widely used. The main compounds contain resin glycosides, terpenoids, phenolic acid, flavonoids, volatile oils, and steroids. Pharmacolog/cal studies have been reported that/, pes-caprae has a variety of pharmacological activities, such as antitumor, antibiosis, anti-inflammatory and analgesic, anticollagenase, anti-oxidation, immun regulation, and other activities. The recent study on chemical composition and pharmacological activities of/. pes-caprae are summarized in this paper to provide reference for the clinical application, quality control and product development of the marine medicine.

关 键 词：厚藤 树脂糖苷 萜类 酚酸类 黄酮类 抗肿瘤活性 抗炎镇痛活性 抗氧化活性 

分 类 号：R282.71[医药卫生—中药学]