胰岛素治疗的糖尿病患者针头重复使用对血糖影响的临床观察  

Effect of needle reuse on blood glucose in diabetic patients treated with insulin

作　　者：王薇[1] 郭晓蕙[1] 申桂菊[1] 白冠男 魏征 

机构地区：[1]北京大学第一医院内分泌科,100034 [2]北京大学医学部公共卫生学院 [3]BD公司

出　　处：《中国糖尿病杂志》2018年第2期101-103,共3页Chinese Journal of Diabetes

摘　　要：目的观察门诊使用胰岛素治疗糖尿病患者针头重复使用的情况及其对血糖的影响。方法入选年龄18~85岁,糖尿病确诊1年以上,目前正在使用胰岛素治疗的门诊患者。研究者对患者进行调查问卷访谈,对胰岛素注射部位进行视诊及触诊的体格检查,判断有无皮下脂肪增生。结果281例患者,注射笔针头重复使用的比例为90.0%。针头使用≥15次者发生脂肪增生的风险是使用1~6次患者的2.69倍(P<0.05)。胰岛素单位体重的日均剂量,针头使用1~6次组低于7~14次组和≥15次组[(0.381±0.231)vs(0.505±0.249)vs(0.509±0.240)IU/(kg·d)](P<0.01)。结论门诊使用胰岛素治疗的糖尿病患者针头重复使用比例高,使用次数越多发生脂肪增生比例越高,需要更多的每日胰岛素剂量。Objective To investigate the influence of repeated use of needle on the blood glucose in diabetic patients treated with insulin in outpatient department. Methods 281 diabetic patients aged 18~ 85 years, diagnosed diabetes for more than I year and treated with insulin were enrolled. Questionnaire was used to collect data. Physical examination was performed to determine if there was subcutaneous fat hyperplasia. Results The percentage of patients who used needle repeatedly was 90.0%. The risk of fat hyperptasia in patients who reused needle ≥15 times for each one was 2.69 times than that in patients who reused needle 1-6 times（P〈0.05）. Insulin daily doses in 1~6 times group were significantly lower than that in 7~14 times and ≥15 times group [（0. 381±0. 231）, （0. 505±0. 249）and （0. 509±0. 240） IU/（kg · d）, respectively, P〈0.01]. Conclusion Diabetic patients treated with insulin at outpatient department have high rates of needle reuse. The risk of fat hyperplasia and the insulin daily dose will be higher when the needles are repeatedly used for more times.

关 键 词：胰岛素 注射针头 血糖 

分 类 号：R587.1[医药卫生—内分泌]