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作 者:蒋继亮 童梁成 谭权昌 夏志强 陈约东 王飞 周强 李颖
机构地区:[1]解放军四五四医院骨一科,江苏南京210002
出 处:《中国临床研究》2018年第2期227-230,共4页Chinese Journal of Clinical Research
基 金:南京军区重点课题项目(2013zd21)
摘 要:目的探讨自主研制的持续皮肤牵伸器治疗皮肤缺损的可行性和效果分析。方法将7只白色家猪的背部(两侧)矩形切除皮肤软组织,创面大小分别为10 cm×5 cm,10 mm×10 mm,制成皮肤缺损模型,共14个创面,分为两组,实验组5只猪10个创面,对照组2只猪4个创面。实验组创面用自制持续皮肤牵伸器行皮肤牵伸治疗,对照组创面只保持创面清洁换药自行愈合。结果使用自制持续皮肤牵伸器组皮肤缺损行3~5 d皮肤伸展术治疗后,可直接行二期缝合关闭,2周后创面愈合。对照组1周后仍存在较大皮肤缺损,无法缝合关闭。实验组创面的每日牵引距离、缩小面积、牵引速度均优于对照组,差异有统计学意义(P均<0.01)。结论应用自制持续皮肤牵伸器行皮肤牵伸术,可以早期快速闭合皮肤缺损创面,且牵伸速度、频次可控,使用方便,效果可靠,并发症少。Objective To explore the feasibility and effect of self-developed skincontinual-stretching device in the treatment of skin defect. Methods The skin defect models were made by rectangular resection of skin and soft tissue in the backs( both sides) of 7 white pigs with 14 wound surface. The mean wound areas of two sides were 10 cm × 5 cm,10 cm ×10 cm. The pigs were divided into experimental group( n = 5,10 wounds) and control group( n = 2,4 wounds). The selfdeveloped skincontinual-stretching device was used for skin traction treatment in experimental group,and wound cleansing and dressing change was used for self healing in control group. Results The skin defects were closed directly by two-stage sutures at 3-5 days after skin traction treatment in experimental group and healed after 2 weeks. However,there were still large skin defects which could not be sutured and closed after 1 weeks in control group. The daily traction distance,shrinking area and drafting speed of the wound in experimental group were obviously better than those in control group( P〈0. 01). Conclusions Skin traction treatment with self-developed skincontinual-stretching device can rapidly close skin defects in early stage,and the speed and frequency of drafting can be controlled. It is easy to use with reliable effect and fewer complications.
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