益气解毒祛瘀法对巨细胞病毒感染大鼠血液流变学的影响  

EFFECT OF YIQI JIEDU QUYU THERAPY ON HEMORHEOLOGY OF RATS INFECTED WITH HUMAN CYTOMEGALOVIRUS

作　　者：秦红松[1] 刘明[1] 孟红[2] 马兴民 张勇[1] 

机构地区：[1]山东中医药大学附属医院,山东济南250011 [2]山东省医学科学院,山东济南250062 [3]潍坊市中医医院,山东潍坊261041

出　　处：《山东中医药大学学报》2002年第5期387-390,共4页Journal of Shandong University of Traditional Chinese Medicine

基　　金：山东省科技厅资助项目 ( 5 2 2 .0 5 7)

摘　　要：为了探讨动脉硬化性闭塞症与人巨细胞病毒感染的关系 ,应用益气解毒祛瘀法 (四妙汤加味 )对感染人巨细胞病毒的大鼠模型进行中药治疗 ,并对血液流变学指标进行检测 ,结果表明人巨细胞病毒感染可引起易栓倾向及血液流变学改变 ,属血瘀证表现。用益气解毒祛瘀法可改善血液循环 ,降低血液黏度 ,防止人巨细胞病毒感染导致血管内皮损伤 ,抑制动脉粥样硬化形成。Evidence suggects that human cytomegalovirus(HCMV)infection may contribute causally to atherosclerosis.In order to investigation of human cytomegalovirus infection as arisk factor for atherosclerosis obliterans,the indexes of thrombosis test in vitro and viscosity in animal models infected with HCMV.AD169 by intravenous injection were measured after treated by Yiqi Jiedu Quyu therapy.Those observation suggest Chinese herbs can promoting blood circulation and decreasing blood hypercoagulability.The properties of HCMV infection are consistent with its involvement at several levers of the atherogenic process.Treatment with Chinese herbs should prevent HCMV infection and atherosclerrosis.

关 键 词：人巨细胞病毒 血液流变学 益气解毒祛瘀 实验研究 动脉硬化性闭塞症 

分 类 号：R259.435[医药卫生—中西医结合]