地佐辛的镇痛作用及其对术后谵妄和躁动的影响  

Analgesic effect of dezocine and its influence on postoperative delirium and agitation

作　　者：程文娟 刘文勋[2] 杨敏[1] 郭宝英 刘佩佩 叶青山[2] 

机构地区：[1]西北民族大学,甘肃兰州730030 [2]宁夏回族自治区人民医院麻醉科,宁夏银川750001

出　　处：《中国新药与临床杂志》2018年第2期70-74,共5页Chinese Journal of New Drugs and Clinical Remedies

基　　金：银川市2016年科技计划项目

摘　　要：术后疼痛不仅延迟患者的术后康复,降低患者生活质量,同时也是术后谵妄等并发症的独立危险因素。地佐辛为一种新型阿片受体部分激动-拮抗剂,有较强的镇痛作用,在临床上广泛应用于术后镇痛。目前大多数研究认为,地佐辛可减轻患者术后谵妄及苏醒期躁动的发生,但这仍需要进一步证实。Postoperative pain not only delays the patients＇ postoperative recovery, reduces the patients＇ quality life, but also plays an independent risk factor for postoperative complications just as delirium. Dezocine,as a new type of opioid receptor partial agonist-antagonist, is widely used in clinical postoperative analgesia because of its strong analgesic effect. At present, most studies suggest that dezocine can reduce the patients＇ postoperative delirium and emergence agitation, but this needs further confirmed.

关 键 词：地佐辛 镇痛 谵妄 苏醒期躁动 

分 类 号：R971[医药卫生—药品]