脓毒性心肌病发病机制研究进展  

Progress of pathogenesis in sepsis-induced cardiomyopathy

作　　者：黎帆 张琪[1] 

机构地区：[1]首都儿科研究所附属儿童医院重症医学科北京协和医学院,北京100020

出　　处：《中国小儿急救医学》2018年第1期52-55,60,共5页Chinese Pediatric Emergency Medicine

基　　金：北京市医管局临床技术创新项目（XMLX201412）

摘　　要：脓毒性心肌病是脓毒症早期出现的可逆性心功能不全，其发病率和病死率逐年提高。全面认识脓毒性心肌病的发病机制对于早期诊断、早期治疗意义重大。本文主要从心肌抑制因子、一氧化氮、细胞代谢障碍、离子失衡等方面对脓毒性心肌病的发病机制研究进展做一综述。Sepsis-induced cardiomyopathy （SIC） is a reversible myocardial dysfunction in the early stage of sepsis. The incidence and mortality of SIC have been increasing in the following years. So it is signif- icant for early diagnosis and treatment to recognize the pathogenesis of SIC. The latest research progress of the pathogenesis of SIC will be stated in this review, from the aspects of myocardial depressant factors, nitric oxide, cellular metabolism disorder, ionic imbalance, etc.

关 键 词：脓毒性心肌病 发病机制 

分 类 号：R459.7[医药卫生—急诊医学]