303例药疹临床研究  

Clinic analysis of 303 cases with drug eruption

作　　者：王思思[1] 宋静卉[1] 周武[1] 

机构地区：[1]河南省人民医院皮肤科,河南郑州450003

出　　处：《中国麻风皮肤病杂志》2018年第1期29-31,共3页China Journal of Leprosy and Skin Diseases

摘　　要：目的:明确我院303例药疹患者的致敏药物。方法:对2006年9月至2016年8月间303例药疹患者的临床资料进行回顾性分析。结果:303例药疹患者中,重症药疹34例,轻中度药疹269例,其中188例患者为发疹型药疹。183例轻中度药疹患者可明确致敏药物,主要致敏药物为抗生素144例,解热镇痛药致敏22例。31例重症药疹患者可明确致敏药物,主要致敏药物为抗癫痫药物11例,抗痛风药物8例,抗生素7例。结论:本院轻中度药疹患者中抗生素类为最常见的致敏药物,重症药疹中抗癫痫药为最常见的致敏药物。Objective： To determine the allergenic drugs in 303 inpatients with drug eruption in our hospital. Methods： The data of 303 patients with drug eruption,diagnosed from September 2006 to August 2016,was analyzed retrospectively. Results： Out of 303 patients,there were 34 patients with severe drug eruption and 269 patients with mild-moderate drug eruptions. Out Of the 269 patients with mild-moderate drug eruptions,exanthematous type（ 188 patients） was the most. The allergenic drugs in 183 patients with mild-moderate drug eruption mainly included antibiotics in 144 patients and analgesic-antipyretic in 22. The allergenic drugs in 31 patients with sever drug eruption mainly included antiepileptic drugs in 11 patients,anti-gout drugs in 8 and antibiotics in another 7. Conclusion： The most common allergenic drugs in the patients with mild-moderate drug eruption were antibiotics and the most common allergenic drugs in the patients with sever drug eruption were antiepileptic drugs.

关 键 词：药疹 致敏药物 

分 类 号：R758.25[医药卫生—皮肤病学与性病学]