不同生长年限重庆庙党3种成分的动态变化  

Study on Dynamic Changes of Three Components of Miaoyu Codonopsis Pilosula at Different Growth Stages

作　　者：杨军宣[1] 郭振宇[1] 张毅 吕志勇[1] 何先元[1] 

机构地区：[1]重庆医科大学中医药学院,重庆400016 [2]重庆市食品药品检验检测研究院,重庆401121

出　　处：《中国现代应用药学》2018年第1期98-102,共5页Chinese Journal of Modern Applied Pharmacy

基　　金：国家药典委员会项目(ZG2016-2-06);重庆市卫生和计划生育委员会中医药科技项目(ZY201702132)

摘　　要：目的研究不同生长年限重庆庙党3种活性成分的动态变化,为庙党的标准化种植、采收及质量控制等提供参考。方法采用UV测定1~5年生重庆庙党多糖及总皂苷的含量变化,采用HPLC测定党参炔苷的含量变化。结果重庆庙党1~4年生长过程中,多糖含量随着生长年限的增加而增大,与第1年比较,第4年增长约100%,第5年增长约90%(第5年与第4年比较,负增长10%);总皂苷及党参炔苷呈逐年递增趋势,第5年总皂苷合计增长约57%,党参炔苷合计增长约42%。重庆庙党生长过程中多糖、总皂苷及党参炔苷三者含量无明显相关性。结论考虑活性成分的增长趋势、生产成本、生产效率、药材产量等因素,重庆庙党种植4年采收即可。OBJECTIVE To study the dynamic changes of three active components of Chongqing Miaoyu Codonopsis pilosula with different growth years, and to provide references for the standardized planting, harvesting and quality control. METHODS UV method was used to determine the content of polysaccharides and total saponins, and HPLC was used to determine the content of lobetyolin. RESULTS In 1-4 years, the content of polysaccharide increased with the increase of growth years. Compared with first year, the content of polysaccharide in fourth year increased about 100%. However, compared with the fourth year, the content decreased about 10% in fifth year. In 1-5 years, the total saponins and the glycosides of codonopsis pilosula increased year by year, compared with first year, total saponins increased by about 57% and lobetyolin increased by about 42% in fifth year. The content growth of polysaccharides, total saponins and lobetyolin were not significantly correlated. CONCLUSION According to the growth trend of active ingredients, production cost, production efficiency and yield of medicinal herbs, Chongqing Miaoyu Codonopsis pilosula should be harvested after 4 years＇ growth.

关 键 词：庙党 生长年限 多糖 总皂苷 党参炔苷 

分 类 号：R285.4[医药卫生—中药学]