聚乙二醇溶液分次剂量法在结肠镜检查肠道准备中的应用  

Application of polyethylene glycol solution split-dose method in intestinal preparation for colonoscopy

作　　者：施茜 杨根源 

机构地区：[1]广东省珠海市人民医院,珠海市519000

出　　处：《护理实践与研究》2018年第4期117-119,共3页Nursing Practice and Research

摘　　要：目的:探讨聚乙二醇溶液(PEG-ES)分次剂量法在结肠镜检测肠道准备中的应用效果。方法:选择我院2016年5~9月的门诊及住院患者4000例,利用高清晰度电子结肠镜施行检查,结肠镜检查前均签署知情同意书,将患者随机等分为A组与B组,A组采用PEG-ELS大容量(4 L)分次剂量,B组采用PEG-ELS大容量(4 L)1次剂量,比较两组患者肠道准备质量评分、不良反应发生率及耐受性。结果:A组患者的左半结肠以及横结肠肠道评分高于B组,差异有统计学意义(P<0.05);两组患者的右半结肠评分差异无统计学意义(P>0.05);A组患者的BBPS总分明显高于B组,差异有统计学意义(P<0.05)。A组患者的恶心、腹胀、腹痛、睡眠障碍的发生率低于B组,差异有统计学意义(P<0.05),两组均无肠穿孔、出血、心肺意外等结肠镜操作不良事件发生;且A组患者认为肠道准备容易完成患者及愿意再次进行肠道准备的患者明显高于B组,差异有统计学意义(P<0.05)。结论:分次剂量给予PEG-ES进行结肠镜准备,较单次给予能取得更满意的肠道清洁效果,患者耐受性好,值得临床推广应用。Objective: To explore the application effect of polyethylene glycol-electrolyte solution( PEG-ES) split-dose method in intestinal preparation for colonoscopy. Methods: A total of 4000 outpatients and inpatients admitted to our hospital from May 2016 to September 2016 were selected. All patients signed informed consent before electron colonoscopy with high definition and they were randomly divided into group A and group B. PEG-ELS large volume( 4 L) split dose was used in group A,while PEG-ELS large volume( 4 L) single dose was used in group B. The intestinal preparation quality score,adverse reaction rate and tolerance between the two groups were compared. Results: The intestinal score of left hemicolon and transverse colon in group A was higher than that in group B,and the difference was of statistical significance( P < 0. 05); the difference was not statistical significance in right hemicolon score between the two groups( P > 0. 05); the total score of BBPS in group A was significantly higher than that in group B,and the difference was of statistical significance( P < 0. 05). The incidence of nausea,abdominal distension,abdominal pain and sleep disturbance in group A was lower than that in group B,and the difference was of statistical significance( P < 0. 05). There were no colonoscopic adverse events such as intestinal perforation,hemorrhage and cardiopulmonary accident in both groups; the number of patients whose intestinal preparation was easy to complete and who were willing to do intestinal preparation again in group A was more than that in group B,and the difference was of statistical significance( P < 0. 05). Conclusion: Fractionation dose of PFG-ES on preparation for colonoscopy could create better Intestinal cleaning effect than single dose of PFG-ES,and patients' tolerance could be satisfactory,so it deserves clinic promotion and application.

关 键 词：结肠镜检查 肠道准备 聚乙二醇电解质溶液 

分 类 号：R473.5[医药卫生—护理学]