哮喘-慢性阻塞性肺疾病重叠综合征患者的全程化药学服务  

Integrated Pharmaceutical Care for Asthma-COPD Overlap Syndrome Patients

作　　者：宋征[1] 郑翠翠[1] 邢树礼[1] 孙绍伟[1] 李保院[1] 

机构地区：[1]滨州医学院附属医院药学部,滨州256603

出　　处：《医药导报》2018年第3期319-322,共4页Herald of Medicine

基　　金：滨州医学院科技计划项目(BY2014KJ42)

摘　　要：目的对哮喘-慢性阻塞性肺疾病重叠综合征(ACOS)患者进行全程化药学服务,减少药物不良反应,提高ACOS患者用药依从性,促进合理用药,降低医疗费用。方法将诊断为ACOS的60例患者随机分为全程化药学服务组(A组)34例与对照组(B组)26例。A组采用全程化药学服务模式,给予院内指导、课堂教学、定期随访、生活指导、心理疏导等;B组不给予干预措施。结果 A组患者对常用药物治疗作用、不良反应的知晓率明显提高;对吸入制剂的掌握情况有较大改善;发生药物不良反应比例显著降低;患者第一秒用力呼气容积(FEV1)以及FEV1增加值明显改善,与B组比较,差异有统计学意义(P<0.05)。A组患者每年医疗总费用、每年抗菌药物费用较B组明显减少,差异有统计学意义(P<0.05)。结论全程化药学服务能够提高ACOS患者用药依从性,改善用药合理性,降低医疗费用。Objective To apply intervention of integrated pharmaceutical care( IPC) for asthma-COPD overlap syndrome patients,so as to reduce the side effects of drugs,enhance medication compliance,promote reasonable drug application,cut down the medical expenses in ACOS patients. Methods A total of 60 ACOS patients were randomly divided into IPC group( group A)( n= 34) and contrast group( group B)( n= 26).The patients in group A were given IPC measurements such as nosocomial guidance,classroom teaching,regular follow-up,life coaching and psychological advice.While the patients in group B were not given any intervention measures. Results In group A,patients' awareness rate of action and side-effects of drugs were obviously increased; Knowledges of inhalation preparation were greatly improved; the ratio of ADRs was significantly reduced; The FEV1 and the value added of FEV1 was dramatically improved.Furthermore,the differences showed statistical significance as compared with group B( P<0.05).Total medical costs and anti-bacterial drug costs per year were significantly lower in group A than group B. Conclusion IPC is beneficial to enhance drug compliance,promote reasonable drug application and bring down the medical expenses in ACOS patients.

关 键 词：临床药师 药学服务 全程化 综合征 重叠 哮喘-慢性阻塞性肺疾病 用药教育 用药依从性 

分 类 号：R969.3[医药卫生—药理学]