血清25-羟维生素D水平与脓毒症关系研究  

Clinical Significance of Serum Level of 25-hydroxyvitamin D in the Patients with Sepsis

作　　者：占凌辉[1] 赖晓勤[1] 檀清照[1] 李娟[1] 

机构地区：[1]福建省厦门大学附属中山医院急诊科,361004

出　　处：《岭南急诊医学杂志》2017年第6期528-530,共3页Lingnan Journal of Emergency Medicine

摘　　要：目的:探讨血清25-羟维生素D水平用于早期评价脓毒症的严重程度判断的意义。方法:61例脓毒症患者入选,根据其临床转归分为死亡组27例,存活组34例。进行急性生理学与慢性健康状况评分Ⅱ(APACHEⅡ),测定患者入住急诊ICU后1 h内的血清25-羟维生素D浓度。采用SPSS17.0软件对结果进行统计学分析。结果:死亡组血清25-羟维生素D水平明显低于存活组(P<0.05),APACHEⅡ评分均明显高于存活组(P<0.05),血清血清25-羟维生素D水平与APACHEⅡ评分呈负相关(r=-0.625,P<0.05)。结论:测定血清25-羟维生素D水平水平有助于早期评价脓毒性患者病情的严重程度。Objective：To investigate the feasibility of 25-hydroxyvitamin D in early evaluating the severity of the patients with sepsis. Methods：61 patients with sepsis were enrolled. According to their different clinical outcomes,the patients were divided into two groups：survival group（34 patients）,death group（27 patients）. APACHE Ⅱ score was calculated and serum level of 25-hydroxyvitamin D was measured within the first 1 h after admission. The results were analyzed with SPSS 17.0 statistical software. Results：The average APACHE Ⅱ score and serum level of 25-hydroxyvitamin D in the death group were higher than those in survival group（P0.05）. There was a linear negative correlation between serum 25-hydroxyvitamin D level and APACHE Ⅱ score（r=-0.625,P0.05）. Conclusion：25-hydroxyvitamin D is a preferable parameter to early evaluate the severity of sepsis.

关 键 词：血清25-羟维生素D 脓毒症 APACHEⅡ评分 

分 类 号：R459.7[医药卫生—急诊医学]