利用PICCO技术评价三七化瘀口服液对严重脓毒血症患者微循环的影响  

The Impact of Notoginseng Compound Oral Liquid on Severe Sepsis Patients Using PICCO

作　　者：戚振红[1] 马明远[1] 邓梦华[1] 张兴胜 马天威[1] 于娜[1] 

机构地区：[1]广州中医药大学附属佛山市中医院ICU,528000

出　　处：《岭南急诊医学杂志》2017年第6期535-537,共3页Lingnan Journal of Emergency Medicine

基　　金：广东省佛山市卫生与计生局医学科研课题(20160028)

摘　　要：目的:评价三七化瘀口服液对于严重脓毒血症患者各项PICCO监测指数的影响。方法:将80例严重脓毒血症病人随机分为对照组与治疗组,每组均40例。两组患者均接受严重脓毒血症集束化治疗方案,治疗组在集束化治疗的方案上给予三七化瘀口服液(20 ml tid),通过统计学方法比较两组患者治疗前后CI、SVRI、ITBVI、GEDVI等指数的差异。结果:两组患者治疗后的CI值较治疗前升高(P<0.05),而SVRI、血乳酸浓度均显著降低(P<0.05),两组患者的ITBVI、GEDVI值在治疗前后比较无统计学差异,但治疗组患者的改善程度优于对照组(P<0.05)。结论:三七化瘀口服液可增加严重脓毒血症患者的CI,降低SVRI、改善微循环状态,具有临床应用价值。Objective：To assess the the impact of Notoginseng compound oral liquid on microcirculation evaluatedby PICCO in Severe sepsis patients. Methods：80 cases of patients with severe sepsis were randomly divided into con-trol groupandtreatment group. The control group（n=40）was received standardized treatment of severe sepsis accordingSSC guidelines. The treatment group（n=40）wasgiven standard treatment plus Notoginseng compound oral liquid（20 ml,three times a day）. The CI、SVRI、ITBVI and GEDVI before and after treatment in both group were recorded andcompare. Results：after the treatment,The CI wereremarkably increased（P0.05）,and the SVRI and blood lactate con-centrations were significantly lower（P0.05）inboth group. There were no differencesbetween ITBVI and GEDVI in bothgroups before and after therapy. Patients in study group was better than that in control group in all PICCO index aftertreatment（P0.05）. Conclusion：Notoginseng compound oral liquid can improve the CI、SVRI index and microcircula-tion state in patients with severe sepsis,it is worthy for clinical application.

关 键 词：PICCO 三七化瘀口服液 严重脓毒症 微循环 CI 

分 类 号：R459.7[医药卫生—急诊医学]