影响单采深度自体储血前后血红蛋白变化的相关因素分析  

Analysis of the factors affecting the variation of hemoglobin value through advanced autologous apheresis

作　　者：吴靖辉[1] 陈冠伊[1] 王丽华[1] 刘圣娥 陈蕾 杨金华[1] 谷立男 卢祝杰 欧阳锡林[1] 

机构地区：[1]解放军总医院第一附属医院输血科,北京100048 [2]承德市第三医院 [3]吉化集团公司总医院第二附属医院

出　　处：《中国输血杂志》2017年第12期1327-1329,共3页Chinese Journal of Blood Transfusion

基　　金：北京市科技计划课题(Z151100003915108)

摘　　要：目的分析择期手术患者深度采集自体浓缩红细胞前后血红蛋白变化的影响因素。方法统计2015.3-2016.4进行术前深度采集4U自体浓缩红细胞的117例患者,记录患者一般资料、采血前后Hb、采血后至手术的时间间隔,通过t检验、单因素分析、多重线性回归分析,总结分析影响患者采血前后Hb变化的影响因素。结果性别因素(女性)是影响采血前后Hb变化的主要影响因素(P<0.001),采血前高Hb也是影响采血前后Hb变化的消极因素(P=0.001),而年龄、体质指数(BMI)、时间间隔均无影响作用。结论符合自体储血适应证的择期手术患者,深度采集自体4U浓缩红细胞后血红蛋白变化量主要与性别密切相关,而不受年龄、体质指数、时间间隔的影响。Objective To analyze the influencing factors of the variation of hemoglobin after blood donation with Advanced Autologous Apheresis（ AAA）. Methods Between March 2015 and April 2016,117 patients who donated 4 units of red blood cells through AAA were conducted. The general demographic of patients,the levels of hemoglobin before and after AAA,the time interval between AAA and operation were investigated,and to summarize the influencing factor in patients through t-test,single factor analysis and multiple linear regression analysis. Results The negative factors were the female and the high level of hemoglobin before AAA（ P≤0. 001）. The age,Body Mass Index（ BMI） and time interval had no affect on the variation of hemoglobin. Conclusion The variation of hemoglobin after AAA is closely associated with the sex,and has nothing to do with the age,BMI and time interval.It is a safe way to donate autologous blood by AAA for the patients undergoing the selective operation.

关 键 词：自体输血 影响因素 多重线性回归 

分 类 号：R457.1[医药卫生—治疗学] R331.141[医药卫生—临床医学]