单试剂阳性献血者屏蔽与归队的可行性分析  

Feasibility analysis of the deferral and reentry of single-ELISA-tested positiveblood donors

作　　者：程玉根 梁启忠 费海燕 

机构地区：[1]盐城市中心血站,江苏盐城224005

出　　处：《中国输血杂志》2017年第12期1376-1378,共3页Chinese Journal of Blood Transfusion

摘　　要：目的了解献血者血液筛查中ELISA法单试剂阳性检测结果假阳性情况,探讨其献血归队的可行性。方法对本地区2015年1月1日-2016年12月31日,251例ELISA法单试剂阳性献血者血液标本进行相应的确证试验;经过6个月以上的献血屏蔽期后,对此前确证试验阴性的部分献血者再次采集标本进行追踪检测,并及时关注符合归队条件的献血者再次献血的情况。结果对251例ELISA法单试剂阳性献血者血液标本进行确证试验,结果有31例确证试验为阳性(阳性率为12.35%);经过6个月以上的献血屏蔽期后,对此前确证试验阴性且主动要求献血归队的87例献血者进行追踪检测,结果仍有11例没有符合献血归队条件,76例成功归队的献血者再次献血的检测结果全部阴性。结论利用ELISA试验和确证试验制定适合的献血者屏蔽与归队方案,能有效地保证受血者临床用血的安全,又能保障献血者无偿献血的合法权益。Objective To evaluatethe false positive cases of blood donors who were tested by only one ELISA test and to discuss the feasibility of their reentry by blood screening. Methods From January 1,2015 to December 31,2016,a total of 251 single-ELISA positive donors were tested by re-confirmatory tests. The partial confirmatory test negative donors were tracked after at least 6 months for deferral. Closerattention was drawn to the reentered donors when they donated blood again.Results 251 positive samples were tested.31（ 12. 35%）,positive cases were identified by confirmatory test. After at least 6 months deferral,87 confirmatory test negative donors requestedreentry and were tracked. 11 cases could not be reentered yet.76 reentered donors were tested to be negative when they donated blood again. Conclusion An improveddeferral and reentry scheme for blood donors can be established based on a combination of ELISA screening and confirmatory tests. It could improve bloodsafety for clinical use and ensure the legal rights of blood donors.

关 键 词：血液筛查 ELISA法 确证试验 献血归队 

分 类 号：R457.1[医药卫生—治疗学] R446.6[医药卫生—临床医学]