肠道菌群对肠粘膜免疫系统影响的研究进展  

Advances in effects of intestinal flora on intestinal mucosal immune system

作　　者：李明美 周艳[1] 李亚齐 黄思思[1] 李小安[1] 

机构地区：[1]成都医学院第一附属医院消化内科"消化系肿瘤与微环境"四川省高校重点实验室,成都610500

出　　处：《生命的化学》2017年第6期895-900,共6页Chemistry of Life

基　　金：四川省教育厅科研项目(16TD0028);四川省医学会科研项目(S16019)

摘　　要：成人肠道内栖息着大量的细菌群落,这些细菌与人体肠粘膜免疫系统协同进化,共同维持肠道内环境稳定。肠道菌群有助于肠道免疫系统的发育和免疫调控,从而保护人机体免受病原体的感染。本文主要阐述肠道菌群对肠粘膜免疫相关的免疫细胞的发育和功能的影响。There are a large number of bacterial communities in the intestinal tract of adults, which could have a co-evolution with human intestinal mucosal immune system, to maintain the balance of the intestinal environment. The intestinal flora contributes to the development and immunoregulation of the intestinal mucosal immune system, thereby protecting the human from infection by pathogens. This paper focuses on the effects of intestinal flora on the development and function of immune cells associated with intestinal mucosal immunity.

关 键 词：肠道菌群 粘膜免疫 发育 功能 

分 类 号：R37[医药卫生—病原生物学]