苍耳子散加味方口服对鼻咽癌放疗患者放射性鼻窦炎的预防作用  

Prevention of radiation sinusitis in patients with nasopharyngeal carcinoma treated with radiotherapy with modified Cangerzi powder

作　　者：屈涛[1] 陈建设[1] 门波[1] 

机构地区：[1]河南省中医院,郑州450002

出　　处：《中药药理与临床》2017年第6期151-154,共4页Pharmacology and Clinics of Chinese Materia Medica

摘　　要：目的:探讨苍耳子散加味方口服对鼻咽癌放疗患者放射性鼻窦炎的预防作用。方法:选取2016年1月~2016年12月我院收治的鼻咽癌放疗患者90例,随机分为两组,对照组应用鼻腔冲洗,观察组联合应用苍耳子散加味方。结果:观察组患者的治疗总有效率显著优于对照组(95.56%比75.56%),同时放射性鼻窦炎发生情况显著低于对照组(24.44%比57.78%)。治疗后,两组患者鼻内镜评分、鼻窦CT评分以及纤毛传输速率均得到一定改善,观察组显著优于对照组[(6.90±0.61)分比(5.11±0.42)分;(11.64±0.42)分比(9.60±0.34)分;(4.67±0.39)分比(3.62±0.35)分]。治疗后两组鼻塞、鼻腔分泌物、头痛、鼻腔黏膜充血均得到一定改善,观察组显著优于对照组[(1.35±0.12)分比(2.10±0.11)分;(1.26±0.15)分比(2.20±0.12)分;(0.41±0.06)分比(0.80±0.09)分;(1.15±0.15)分比(2.12±0.13)分]。结论:鼻咽癌放疗患者口服应用苍耳子散加味方有利于预防放射性鼻窦炎,改善患者鼻窦功能。Objective： To study the preventive effect of modified Cangerzi powder on radiation sinusitis in patients with nasopharyngeal carcinoma treated with radiotherapy. Methods： Ninety patients with nasopharyngeal carcinoma treated in our hospital from January 2016 to December2016 were randomly divided into two groups. Patients in the control group were treated with nasopharyngeal irrigation,those in the observation group received nasopharyngeal irrigation combined with modified Cangerzi powder. Results： The total effective rate in the observation group was significantly better than that in the control group（ 95. 56% vs 75. 56%）,and the incidence rate of radioactive sinusitis was significantly lower than that in the control group（ 24. 44% vs 57. 78%）（ P〈0. 05）. Endoscopic score,paranasal sinus CT score and mucociliary transport rate in two groups were better than those before the treatment（ P〈0. 05） and those in the observation group were significantly better than those in the control group[（ 6. 90 ± 0. 61） points vs（ 5. 11 ± 0. 42） points;（ 11. 64 ± 0. 42） points vs（ 9. 60 ± 0. 34） points;（ 4. 67 ± 0. 39）points vs（ 3. 62 ± 0. 35） points]（ P〈0. 05） respectively. Nasal congestion,nasal secretions,headache and Congestion of nasal mucosa in two groups were better improved than those before the treatment（ P〈0. 05） and those in the observation group were more significantly improved than those in the control group[（ 1. 35 ± 0. 12） points vs（ 2. 10 ± 0. 11） points;（ 1. 26 ± 0. 15） points vs（ 2. 20 ± 0. 12） points;（ 0. 41 ± 0. 06）points vs（ 0. 80 ± 0. 09） points;（ 1. 15 ± 0. 15） points vs（ 2. 12 ± 0. 13） points ]（ P〈0. 05）. Conclusion： The application of Xanthium sibiricum for patients with nasopharyngeal carcinoma treated with radiotherapy is beneficial to prevent radioactive sinusitis and improve the function of sinus function.

关 键 词：苍耳子散加味方 鼻咽癌放疗 放射性鼻窦炎 

分 类 号：R273[医药卫生—中西医结合]