腹膜透析治疗儿童急性肾损伤的有效性和安全性评价  

Efficacy and safety of peritoneal dialysis in pediatric acute kidney injury

作　　者：耿海云[1] 陈朝英[1] 涂娟[1] 李华荣[1] 保睿[1] 杜培玮 于晓宁[1] 

机构地区：[1]首都儿科研究所附属儿童医院肾脏内科,北京100020

出　　处：《中国医刊》2018年第2期189-191,共3页Chinese Journal of Medicine

摘　　要：目的探讨腹膜透析治疗儿童急性肾损伤的临床疗效及安全性。方法选取2007年3月至2016年3月于本院住院应用腹膜透析治疗的12例急性肾损伤患儿,比较腹膜透析治疗前后的血肌酐、尿素、血气、血钾、血钠、血白蛋白、尿量、体重、血压等指标变化。结果腹膜透析3天时,血肌酐、尿素、p H值、碳酸氢根、白蛋白、尿量、体重等指标与透析前比较均有显著好转(P<0.05)。1例高血钾患儿及8例低血钠患儿中的6例均于透析3天内指标恢复正常,另2例血钠恢复至接近正常。4例肾功能完全恢复拔腹透管,5例因慢性肾小球疾病继续维持腹膜透析治疗,1例转外院行血浆置换,2例自动出院。结论应用腹膜透析治疗儿童急性肾损伤疗效肯定,安全性好。Objective The aim of this study was to investigate the efficacy and safety of peritoneal dialysis in peadiatric acute kidney injury. Method 12 patients who were admitted in our Hospital from March 2007 to March 2016 underwent acute kidney injury treated with peritoneal dialysis were recruited, clinical data including biochemistry indices were compared. Result After PD treatment, their blood creatinine, urea,p H,bicarbonate, albumin,urine output, body weight were improved just in 3 days（P〈0.05）.1 case with hyperkalemia and 6 cases with hyponatraemia recovered to nomal level, another 2 cases with hyponatraemia improved also.4 patients recovered and removed tubular,5 cases remained on PD because of CKD.1 case referral to other hospital for plasma exchange, 2 cases discharged without recovery. Conclusion PD is effective and safe for AKI in pediatrics.

关 键 词：腹膜透析 急性肾损伤 儿童 

分 类 号：R720.5[医药卫生—儿科]