呼出气一氧化氮及潮气肺功能检测在婴幼儿喘息性肺炎中的临床意义  

Clinical study of exhale nitric oxide and tidal breath pulmonary function in infants with wheeze pneumonia

作　　者：张蕾 艾涛 罗荣华 王莉 夏万敏 樊映红 

机构地区：[1]成都市妇女儿童中心医院呼吸科,610007

出　　处：《国际呼吸杂志》2018年第3期204-206,共3页International Journal of Respiration

摘　　要：目的探讨呼出气一氧化氮（FeNO）及潮气肺功能检测在婴幼儿喘息性肺炎中的意义。方法选取成都市妇女儿童中心医院诊断社区获得性肺炎儿童，入院当天完成FeNO、潮气肺功能检测及皮肤点刺过敏原检测，分为喘息性肺炎组，非喘息性肺炎组，比较两组之间的差异。结果喘息性肺炎组患儿FeNO、达峰时间比、达峰容积比及过敏原阳性率均高于非喘息性肺炎患儿，差异有统计学意义（P〈0．05）。FeNO与达峰时间比（tPTEF／tE）及达峰容积时间比（vPTEF／vE）无相关性。结论FeNO及潮气通气肺功能可从气道炎症及气道损伤两方面综合对喘息性肺炎儿童进行临床管理。Objective To investigate the clinic significance of fractional exhaled nitric oxide （FeNO） and tidal breath pulmonary function in infants with wheeze pneumonia. Methods The results of FeNO, tidal breath pulmonary function and skin prick test of the breathing group and the control group got on the first day of hospitalization were analyzed. Results The values of FeNO, the time necessary to reach the peak expiratory flow in tidal breathing over the total expiratory time （tPTEF/tE）, the volume nexessory to reach the peak expiratory flow in tidal breathing over the total expiratory flow （vPTEF/vE） of breathing group were significantly higher than the control group （ P 〈0.05）. The values of FeNO had no correlation with tPTEF/tE and vPTEF/vE. Conclusions FeNO and tidal breath pulmonary function can provide the basis of airway inflammation and damage which can help the clinical management.

关 键 词：婴幼儿 喘息性肺炎 呼出气一氧化氮 潮气肺功能 

分 类 号：R725.6[医药卫生—儿科]