HPLC指纹图谱在中药制剂质量研究中的应用  

Application of HPLC Fingerprint in Quality of Traditional Chinese Medicine Preparations

作　　者：叶婷 梁文仪[1] 梁林金 李师[1] 吴玲芳[1] 亓旗 崔雅萍[1] 陈文静[1] 张兰珍[1] 

机构地区：[1]北京中医药大学中药学院,北京100102

出　　处：《世界科学技术-中医药现代化》2017年第11期1794-1800,共7页Modernization of Traditional Chinese Medicine and Materia Medica-World Science and Technology

基　　金：国家自然科学基金面上项目:基于藏药余甘子酚酸类成分体内动态变化的抗癌药效物质与质量控制研究(81274187);负责人:张兰珍

摘　　要：高效液相色谱指纹图谱技术是中药制剂质量控制的重要手段,可较全面地反映原料药材、制剂工艺全过程及成品的质量,已成为现代中药制剂质控的重要方法。本文主要对近几年HPLC指纹图谱及其联用技术在中药制剂质量控制过程中的研究进展进行综述,为中药制剂后期质量控制研究提供依据。High performance liquid chromatography（HPLC） fingerprint technology is an important means of quality control of traditional Chinese medicine（TCM） preparations, which can reflect the whole process of raw materials as well as the whole process and quality of finished products. It has become the primary quality control method of modern TCM preparations. In this paper, recent advances in HPLC fingerprints and their combination techniques in the quality control of TCM preparations were reviewed, which provided the basis for quality control of TCM preparations.

关 键 词：高效液相色谱 指纹图谱 中药制剂 质量控制 

分 类 号：R284[医药卫生—中药学]