针刺联合间充质干细胞移植的实验研究进展  

Experimental Research Progress of Acupuncture Combined with Mesenchymal Stem Cells Transplantation

作　　者：李天然[1,2] 叶阳 王雪蕊 姬彩硕[1] 王宇 刘存志 

机构地区：[1]首都医科大学附属北京中医医院针灸中心首都医科大学附属北京中医医院针灸神经调控北京市重点实验室,北京100010 [2]天津中医药大学研究生院,天津300193

出　　处：《世界科学技术-中医药现代化》2017年第11期1868-1871,共4页Modernization of Traditional Chinese Medicine and Materia Medica-World Science and Technology

基　　金：国家自然科学基金面上项目:针刺改善血管性痴呆大鼠认知功能的多巴胺/肾上腺素受体机制研究(81473501);负责人:刘存志

摘　　要：间充质干细胞(mesenchymal stem cells,MSCs)是机体的起源细胞,是形成人体各种组织器官的始祖细胞。因其具有自我复制和多向分化的能力,可在特定条件下转变成为多种构成人体组织或器官的细胞。针刺联合MSCs移植的研究已取得了一定的进展,显示出潜在的应用前景。本文整理、总结了近10年来针刺联合MSCs移植疗法的实验研究文献,以治疗不同种类疾病为切入点,综述目前针刺联合MSCs移植疗法的基础实验研究进展。针刺联合MSCs移植的生物学机制可能与针刺能增加MSCs的存活率、诱导MSCs定向分化有关。但是,针刺联合MSCs移植要作为一项常规技术应用于临床实践,其内在机制尚需进一步研究阐明。Mesenchymal stem cells（MSCs）, progenitor cells with the ability of self replication and differentiation, are able to change into many kinds of cells or tissues. The study of acupuncture combined with MSCs transplantation has made some progress and shown potential application prospect. This article summarized experimental research literatures of acupuncture combined with MSCs transplantation over the past ten years. Biological mechanisms of acupuncture combined with MSCs transplantation might be related to the increase of MSCs survival rate and the directional differentiation of MSCs induced by acupuncture. The combination of acupuncture and MSCs transplantation might be used as a potential routine technique in clinical practice. The underlying mechanisms still need to be further elucidated.

关 键 词：针刺 间充质干细胞 实验研究 进展 

分 类 号：R55[医药卫生—血液循环系统疾病]