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机构地区:[1]北京医院皮肤科国家老年医学中心,100730
出 处:《实用皮肤病学杂志》2017年第6期337-339,共3页Journal of Practical Dermatology
摘 要:目的调查慢性皮炎湿疹患者常见的接触性变应原,并探讨其与临床特征之间的相关性。方法回顾性分析2011年7月—2016年7月在皮肤科门诊就诊的1 058例慢性皮炎湿疹患者的斑贴试验结果,应用统计学方法比较变应原阳性率与患者的性别、年龄、病程、皮损发生部位和个人过敏史的相关性。结果斑贴试验总阳性率为38.6%,女性阳性率高于男性;60岁以下(非老年组)阳性率高于60岁以上(老年组);有个人过敏史、皮损泛发和病程长(≥3年)的患者阳性率更高。男性患者重铬酸钾、对苯类混合物和卡巴混合物3种变应原的阳性率高于女性;老年组卡巴混合物的阳性率高于非老年组,而硫酸镍的阳性率低于非老年组。结论慢性皮炎湿疹患者斑贴试验的总阳性率<40%;变应原阳性率的高低与患者的性别、年龄、病程、个人过敏史及发病部位有一定关联。Objective To investigate the prevalence of common allergens among chronic dermatitis/eczema patients and the correlation between these common allergens and patients' gender, age, and clinical characteristics. Methods A total of 1058 outpatients with chronic dermatitis/eczema in Department of Dermatology, Beijing Hospital, accepted patch test with Rui min standard allergens series from July 2011 to July 2016. Corresponding statistical methods were used to analyze respectively the correlation between the positive rate of allergens and patients' gender, age, duration of the disease, location and distribution of the lesions, and individual history of allergy. Results The overall positive rate of tested allergens for the 1058 patients was 38.6%. The female, non-elderly patients(less than 60 years old) or patients with individual history of allergy, generalized rash or longer duration of the disease(above 3 years) had higher positive rate of tested allergens than males, elderly patients(above 60 years old) or those without history of allergy, non-generalized rash or short duration(less than 3 years). Male patients had higher positive rate for potassium dichromate, parabensin, and carba mix compared to female patients. The patients in elderly group had higher positive rate for carba mix and lower positive rate for nickel sulfate compared to non-elderly group. ConclusionThe total positive rate of patch test in chronic dermatitis/eczema patients was less than 40%. The positive rates of total and several common allergens were related to patients' gender, age, duration of the disease, individual history of allergy, and the distribution of the lesions.
分 类 号:R758.23[医药卫生—皮肤病学与性病学]
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