三种人工阴道成形术后阴道优势菌群和乳酸杆菌调查  

Study of vaginal predominant bacteria and Lactobacilli in three kinds of vaginoplasty

作　　者：鲁丽丽[1] 刘建华[1] 

机构地区：[1]上海交通大学医学院附属第九人民医院妇产科,上海200011

出　　处：《中国医药导报》2018年第5期98-102,共5页China Medical Herald

摘　　要：目的研究结肠代阴道、皮肤代阴道及COOK生物补片代阴道这三种人工阴道成形术后阴道优势菌群和乳酸杆菌定植情况。方法选择2014年1月~2016年1月在上海交通大学医学院附属第九人民医院施行阴道成形术患者为研究对象,其中结肠代阴道、皮肤代阴道及COOK生物补片代阴道术患者各12例。分别于术后1个月、术后6个月及术后1年取其阴道分泌物,选用不同的细菌培养基进行培养从而得出阴道优势菌群,并检测这三种人工阴道内是否有乳酸杆菌定植。结果三种人工阴道成形术后阴道优势菌群各不相同,术后1个月、术后6个月及术后1年部分患者阴道优势菌存在变异,4例结肠代阴道及3例COOK生物补片代阴道的患者人工阴道内检测出乳酸杆菌。结论三种人工阴道成形术后阴道优势菌群呈现各自特点,部分结肠代阴道及COOK生物补片代阴道的人工阴道内检测到有乳酸杆菌定植,这些患者的阴道微生态环境可能更趋近于正常女性。Objective To investigate the vaginal predominant bacteria distribution and the existence of Lactobaeilli after sigmoid vaginopalsty, skin graft vaginoplasty and COOK soft tissue graft vaginoplasty. Methods Twelve women with sigmoid vaginopalsty, 12 women with skin graft vaginopalsty and 12 women with COOK soft tissue graft vaginopalsty from January 2014 to January 2016 in Shanghai Ninth People＇s Hospital Affiliated to School of Medicine of Shanghai JiaoTong University. These patients underwent vaginopalsty were selected. The vaginal discharge in the eases were colleered respectively at 1 month, 6 months and 1 year after vaginopalsty. Various kinds of bacteria culture media were used to identify the predominant bacteria and to detect vaginal Laetobacilli in the eases. Results The predominant bacteria distributions in the three kinds of artificial vagina were different. The species of vaginal predominant bacteria varied at 1 month, 6 months and 1 year after vaginopalsty in some eases. Vaginal Lactobacilli had been found in 4 women with sigmoid vaginopalsty and 3 women with COOK soft tissue graft vaginopalsty. Conclusion The vaginal predominant bacteria distributions after the three kinds of vaginoplasty present their respective characteristics. Several patients with sigmoid vaginopalsty and with COOK soft tissue graft vaginopalsty have Lactobaeilli in their artificial vagina. These patients＇ vaginal microecologieal environment may be closer to that of healthy women.

关 键 词：结肠代阴道 皮肤代阴道 COOK生物补片代阴道 阴道优势菌 乳酸杆菌 

分 类 号：R713.31[医药卫生—妇产科学]