乳酸酸中毒的相关研究进展  

Relevant research progress of lactic acidosis

作　　者：胡宝吉 薄禄龙[2] 邓小明[2] 段宏伟 

机构地区：[1]上海市浦东医院暨复旦大学附属浦东医院麻醉科,上海201399 [2]上海长海医院麻醉科,上海200433

出　　处：《中国医药导报》2018年第3期22-25,共4页China Medical Herald

基　　金：国家自然科学基金资助项目(81671887、81471845、81701885);上海市卫生系统优秀青年人才培养计划项目(2017YQ015);上海市浦东医院“浦秀计划”人才培养项目(PX201401)

摘　　要：乳酸是体内碳水化合物和非必需氨基酸非常重要的中间代谢产物,重症患者血中乳酸浓度升高的水平对患者预后甚至病死率有着重要的警示作用。本文通过综述乳酸酸中毒的临床意义及潜在的治疗方法,阐明乳酸对机体的作用及其对疾病预后的潜在意义,为重症疾病治疗提供新的思路。Lactate is one of the most crucial intermediates in carbohydrate and nonessential amino acid metabolism, in addition, the presence of elevated lactate levels in critically ill patients has important implications for prognosis and mortality. The paper reviews the clinical role of lactic acid and the potential treatments, elucidates the important role and prognostic significance of lactic acid and provides new thoughts for the therapies of severe diseases.

关 键 词：乳酸代谢 乳酸酸中毒 脓毒症 

分 类 号：R58[医药卫生—内分泌]