新生儿导管相关血流感染危险因素分析  

Analysis of risk Factors for Catheter-related Bloodstream Infection In Neonates

作　　者：谢建宁[1] 高平明[1] 黄朝梅[1] 王兆莉[1] 

机构地区：[1]南方医科大学附属佛山市妇幼保健院,广东佛山528000

出　　处：《实用医学杂志》2018年第4期618-620,共3页The Journal of Practical Medicine

基　　金：佛山市科技局基金资助项目(编号:2014AB00383)

摘　　要：目的探讨新生儿经外周中心静脉置管(PICC)引起的血管内导管相关感染(CRBSI)发生率、危险因素及病原学特点。方法回顾2015、2016年两年内收住我院新生儿病房并施行PICC的患儿640例,对CRBSI的危险因素进行分析。结果施行PICC的640例新生儿中有9例发生CRBSI,CRBSI发生率为0.60/1 000导管日(10/15 087)。发生CRBSI的危险因素包括使用碳青霉烯类抗菌药物、机械通气史(P<0.05)。在检出的病原体中,真菌为主,占80.00%,其次为葡萄球菌,占20.00%。结论新生儿发生CRBSI的危险因素为碳青霉烯类抗菌药物的使用和机械通气的使用,致病菌大多为真菌和葡萄球菌。Objective To investigate the CRBSI rate, risk factors and etiological of PICC in neonates. Methods This is a retrospective case-serials analysis of 640 in-patients of newborn babies with PICC in our Hospital from 2015 to 2016, all the cases received PICC catheter treatment, and the factors of catheter-related bloodstream infections were analyzed. Results The number of PICC catheter-related bloodstream infection was 9, CRBSI rate pet 1000 central line-days was 0.60. The risk factors for CRBSI include the usage of Carbapenem antibiotic and the invasive mechanical ventilation （P 〈 0.05）. The ratio of fungal, Staphylococcus in CRBSI was 80.00 % and 20.00%, respectively. Conclusion Possible risk factors which cause CRBSI are the usage of Carbapenem antibiotic and the invasive mechanical ventilation. The major pathogen was fungal.

关 键 词：经外周中心静脉置管 血管内导管相关感染 新生儿 危险因素 

分 类 号：R722.13[医药卫生—儿科]