阴虚体质不育患者行ICSI结局相关指标的临床观察研究  

Observational study on the outcomes of ICSI for infertile patients with Yin-deficient constitution

作　　者：马春晓[1,2] 谢雅兰 胡海翔[1] 徐少强[1] 孙哲[1] 

机构地区：[1]中国人民解放军空军总医院中西医结合男科,北京100142 [2]北京中医药大学东直门医院生殖内分泌科,北京100029 [3]北京市门头沟区妇幼保健院孕产保健部,北京102300

出　　处：《中国性科学》2018年第2期95-98,共4页Chinese Journal of Human Sexuality

基　　金：2016年度军队计生专业科研课题项目(16JS004)

摘　　要：目的:临床观察阴虚体质患者行ICSI助孕技术的妊娠结局,探讨男性不育症的中医诊疗新思路。方法:根据中华中医药学会2009年4月实施的《中医体质分类与判定》(ZYYXH/T157-2009)对66例不育男性行ICSI助孕技术患者进行体质辨识,结合临床资料进行统计分析。结果:阴虚体质不育患者的正常受精率显著低于平和体质正常受精率,具有显著的统计学差异(P<0.01);平和体质优质胚胎率明显高于阴虚体质,差异具有统计学意义(P<0.05);而在获卵数、成熟卵数、受精率、移植胚胎个数、胚胎形成率、临床妊娠率、生化妊娠率方面,两组间比较无统计学差异(P>0.05)。结论:阴虚体质不育人群男性生育能力与行ICSI助孕技术相关指标较平和体质不育人群低下。Objectives： To evaluate the outcome of pregnancy after receiving the ICSI for infertile patients who were Yin-deficient constitution,in order to explore an original treatment for male infertility. Methods： The constitution of 66 infertile patients was classified according to the Classification and Determination of Traditional Chinese Medicine issued by the China Association of Chinese Medicine in April 2009. All the 66 patients received ICSI and were surveyed and the clinical data was analyzed. Results： The normal fertilization rate and high quality embryo rate of patients with Yin-deficient constitution was significantly lower than those of patients with mild constitution,with statistical significance（ P〈0. 01,P〈0. 05）. However,differences in fertility rate,number of retrieved oocytes,the number of the maturation oocytes,the number of the embryos,the rate of biochemical pregnancy and clinical pregnancy rate were not significant（ P〈0. 05）. Conclusion： The indicators and outcomes of male patients with Yin-deficient constitution were relatively lower than those of patients with mild constitutions.

关 键 词：男性不育症 体质 ICSI 妊娠结局 

分 类 号：R256[医药卫生—中医内科学]