多发性硬化伴发记忆障碍MRI研究进展  

Research progresses of MRI in multiple sclerosis with memory impairment

作　　者：顾瑶 李咏梅[1] 付佳亮 韩永良[1] 廖旦[1] 

机构地区：[1]重庆医科大学附属第一医院放射科,重庆400016

出　　处：《中国医学影像技术》2018年第3期444-447,共4页Chinese Journal of Medical Imaging Technology

基　　金：国家自然科学基金面上项目(81371523);重庆市卫生计生委医学科研计划项目(2016ZDXM002)

摘　　要：多发性硬化(MS)是以中枢神经系统炎性脱髓鞘改变为主要表现的疾病,是中青年非创伤性神经功能残疾的主要原因,主要表现为记忆及信息处理速度、执行功能等多种认知领域障碍。MS伴发记忆障碍(MSMI)因发病隐匿而常被忽略,严重影响患者生活质量。随着神经功能影像学的快速发展,MRI已成为观察和诊断MS的重要手段,可为诊断MSMI提供影像学依据。本文就MSMI相关临床及MRI研究进展进行综述。Multiple sclerosis （MS） is a disease characterized as inflammatory demyelinating of the central nervous system, which is the main cause of non-traumatic neurological disability in young and middle-age adults. The main manifestations of MS are memory and information processing speed, executive function and other cognitive impairments. MS associated with memory impairment （MSMI） is often overlooked because of the occult onset, which seriously affecting patients＇ life quality. In recent years, with the rapid development of neuro-functional imaging, MRI has become an important method to observe and diagnose MS, providing imaging evidence for diagnosis of MSMI. The clinical and MRI research progresses of MEMI were reviewed in this article.

关 键 词：多发性硬化 记忆障碍 磁共振成像 

分 类 号：R445.2[医药卫生—影像医学与核医学] R744.51[医药卫生—诊断学]