综合疗法治疗刺激性气体中毒临床疗效分析  

Analysis of the clinical efficacy of comprehensive therapy in the treatment of irritant gas poisoning

作　　者：唐雪飞 

机构地区：[1]大连市第四人民医院职业病一病房,116000

出　　处：《中国现代药物应用》2018年第5期18-19,共2页Chinese Journal of Modern Drug Application

摘　　要：目的观察综合疗法对刺激性气体中毒患者的临床疗效。方法 36例刺激性气体中毒患者均采用综合疗法治疗,检测不同中毒分级患者治疗前后的动脉血氧分压(PaO_2)、动脉血二氧化碳分压(PaCO_2)和血氧饱和度(SpO_2)水平变化情况。结果治疗前,随着中毒程度的加深,PaO_2和SpO_2逐渐下降,PaCO_2逐渐上升,差异具有统计学意义(P<0.05)。治疗后轻度中毒患者的PaCO_2(37.9±1.0)mm Hg(1mm Hg=0.133 k Pa)显著低于治疗前的(39.9±1.0)mm Hg,差异具有统计学意义(P<0.05)。治疗后中度中毒患者和重度中毒患者的PaO_2、PaCO_2和SpO_2均优于治疗前,差异具有统计学意义(P<0.05)。结论综合疗法对刺激性气体中毒疗效较好,尤其针对重度患者,值得临床推广。Objective To observe the clinical efficacy of comprehensive therapy in the treatment of irritant gas poisoning.Methods A total of 36 patients with irritant gas poisoning were treated by comprehensive therapy.The changes of arterial oxygen partial pressure（PaO2）,arterial carbon dioxide partial pressure（PaCO2） and blood oxygen saturation（SpO2） level were measured before and after treatment.Results Before treatment,with the deepening of poisoning,PaO2 and SpO2 gradually decreased,and PaCO2 gradually increased.The difference was statistically significant（P〈0.05）.After treatment,mild poisoning patients had obviously lower PaCO2 as（37.9±1.0） mm Hg（1 mm Hg=0.133 kPa） than（39.9±1.0） mm Hg before treatment,and the difference was statistically significant（P〈0.05）.After treatment,moderate and severe poisoning patients had better PaO2,PaCO2 and SpO2 than before treatment,and their difference was statistically significant（P〈0.05）.Conclusion Comprehensive therapy shows a good effect on irritant gas poisoning,especially for severe patients,and it is worthy of clinical promotion.

关 键 词：综合疗法 刺激性气体中毒 

分 类 号：R595.1[医药卫生—内科学]