孕妇TORCH感染影响因素分析及对妊娠结局的影响  

Influencing factors of TORCH infection in pregnant women and impact on pregnancy outcomes

作　　者：夏钟意 孙博[1] 吴红珍[1] 冷建航 

机构地区：[1]杭州市第一人民医院中心实验室,浙江杭州310000

出　　处：《中国妇幼健康研究》2018年第2期218-220,共3页Chinese Journal of Woman and Child Health Research

摘　　要：目的探究孕妇TORCH感染情况、影响因素及对妊娠结局的影响。方法选取2015年3月至2017年8月在杭州市第一人民医院接受产检的1 000例孕妇,对其进行TORCH检验,同时采用问卷调查的方式收集影响TORCH感染发生的因素,计数资料及单因素分析采用χ~2检验,采用Logistic回归方法进行多因素分析,对比TORCH感染组与无感染组孕妇不良妊娠结局。结果 1 000例孕妇中检出79例TORCH感染者,将其作为感染组,总感染率7.90%,其中风疹病毒(RV)感染15例(1.50%)、弓形虫(TOX)感染5例(0.50%)、巨细胞病毒(CMV)感染35例(3.50%)、单纯疱疹病毒I型(HSV)感染11例(1.10%)、单纯疱疹病毒Ⅱ型(HSVⅡ)感染13例(1.30%);在上述几项病毒感染中以CMV感染居多。对1 000例孕妇女进行TORCH相关因素分析发现,TORCH感染与孕妇的年龄、受教育程度、家庭背景、动物接触史、妊娠异常史、收入水平有明显的相关性(χ~2值分别为8.07、12.53、5.88、19.11、112.70、7.56,均P<0.05)。进行多因素Logistics回归方程分析显示,年龄、家庭背景、动物接触史、妊娠异常史是孕妇TORCH发生的高危因素(Waldχ~2值分别为8.77、7.82、9.81、19.36,均P<0.05),受教育程度是保护因素(Waldχ~2=29.12,P<0.05)。在不良妊娠结局方面,感染组宫内感染、早产、流产、胎儿发育迟缓及新生儿死亡的发生率显著高于无感染组(χ~2值分别为46.51、20.47、14.93、38.54、24.85,均P<0.05)。结论年龄、受教育程度、家庭背景、动物接触史、妊娠异常史是影响孕妇感染TORCH的重要因素,此外TORCH感染与不良妊娠的发生密切相关,是不良妊娠结局的危险因素。Objective To investigate the TORCH infection in pregnant women,its influencing factors and the impact on pregnancy outcomes.Methods Totally 1 000 pregnant women for TORCH test were selected in Hangzhou First People＇s Hospital from March2015 to August 2017.At the same time,aquestionnaire was used to collect the factors influencing TORCH infection,andχ~2 test was used for counting data and univariate analysis.Multivariate logistic regression analysis was used to compare the adverse pregnancy outcomes in TORCH infection group and non-infection women.Results Among 1 000 pregnant women selected for TORCH-IgM antibody detection,79 cases were detected with TORCH infection and they were in infection group.The total infection rate was 7.90%.There were 15 cases of RV infection（1.50%）,5 cases of TOX infection（0.50%）,35 cases of CMV infection（3.50%）,11 cases of HSV Ⅰ infection（1.10%）and 13 cases of HSV Ⅱ infection（1.30%）.Among the above viral infections,most of them were infected with CMV.TORCH related factors analysis of 1 000 pregnant women found that TORCH infection was correlated with age,education level,family background,animal exposure history,abnormal pregnancy history and income level of pregnant women（χ~2 value was 8.07,12.53,5.88,19.11,112.70 and 7.56,respectively,all P0.05）.Logistic regression analysis of multiple factors showed that age,educational level,family background,animal exposure history and abnormal pregnancy history were the high-risk factors of TORCH in pregnant women（χ~2 value was 8.77,7.82,9.81 and 19.36,respectively,all P0.05）,and that the level of education was a protective factor（χ~2=29.12,P0.05）.In adverse pregnancy outcomes,the incidence of intrauterine infection,premature birth,abortion,fetal retardation and neonatal death was significantly higher in infection group than in non-infection group（χ~2 value was 46.51,20.47,14.93,38.54 and 24.85,respectively,all P0.05）.Conclusion Age,education level,family background,animal exposure history and history

关 键 词：TORCH 受教育程度 妊娠异常史 不良妊娠结局 

分 类 号：R714.2[医药卫生—妇产科学]