临床电解质分析用标准物质的研制及应用  

Development and application of standard reference material in clinical electrolyte analysis

作　　者：吴国强 丁海铭[2] 陈国松 

机构地区：[1]深圳市凯特生物医疗电子科技有限公司,广东深圳518053 [2]黑龙江省计量检定测试院,黑龙江哈尔滨150036 [3]南京工业大学化学与分子工程学院,江苏南京210009

出　　处：《化学传感器》2017年第4期56-59,共4页Chemical Sensors

摘　　要：介绍了高、中、低三种浓度水平的人血清无机成分电解质标准物质的研制过程和应用范围。基于该标准物质主要应用于临床检验,除对标准物质的原料选择和处理、均匀性、稳定性进行评定外,还对该标准物质的定值方法和基质效应与互通性进行了评估。研制的人血清无机成分电解质标准物质可用于临床电解质分析的量值溯源、电解质分析仪的检定和校准、方法评价及质量控制等。This paper discusses the development and application of standard reference material（SRM） in low,medium,and high concentration for inorganic components of electrolytes in human serum. Considering the popular application of SRM in clinical laboratory, this paper evaluates not only the selection and process of SRM, its homogeneity and stability, but also its certificating mothod, matrix effect and interoperability. SRM for inorganic components of electrolytes can be applied in traceability of clinical electrolyte analysis, verification and calibration of clinical electrolyte analyzer as well as mothod evaluation and quality control.

关 键 词：标准物质 临床检验 电解质分析 人血清 计量学 

分 类 号：R446[医药卫生—诊断学]